Anti-Human LRRN1 Recombinant Antibody Fab Fragment (TB0777#281-6 (N1mAb))
CAT#: TAB-522MZ-F(E)
This antibody may provide a therapeutic agent and a therapeutic method for cancers including neuroblastoma, pulmonary cancer, mammary cancer, etc. Another purpose this product is to provide a cancer diagnostic agent and an imaging agent.
Published Data
Gene Expression
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Figure 1 A is a SY5Y-ctrl, B is a result of SY5Y-N1.
It shows cell growth inhibitory effect of anti NLRR1 monoclonal antibody (NLRR1 mAb # 281-6) in NB and non NB cells.
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Figure 2 It shows that the treatment with N1mAb antibody (# 281-6) was significantly inhibited the growth of xenograft tumors.
Open circles are saline, the black circles is an antibody.
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Figure 3 It shows that the treatment with N1mAb antibody (# 281-6) was significantly inhibited the growth of xenograft tumors.
Open circles are saline, the black circles is an antibody.
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Normal Tissue
Figure 1 IHC staining of human cerebral cortex
High expression. RNA expression: 7.2 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_B_8_5_val_selected.jpg
Normal Tissue
Figure 2 IHC staining of human lymph node
Low expression. RNA expression: 0.3 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_8_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranou
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (AF22, CAPAN-2, HAP1, NTERA-2, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000175928-LRRN1
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Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- TB0777 # 281-6 (N1mAb)
- Applications
- ELISA, FC, Inhib, FuncS
- Related Disease
- Cancers including neuroblastoma, pulmonary cancer, mammary cancer
Applications
- Application Notes
- The antibody was validated for Inhibition and Function assay. For details, refer to Published Data.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone TB0777 # 281-6 (N1mAb)"
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See other products for "LRRN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-522MZ | Anti-Human LRRN1 Recombinant Antibody (TB0777#281-6 (N1mAb)) | ELISA, FC | |
| TAB-522MZ-S(P) | Anti-Human LRRN1 Recombinant Antibody scFv Fragment (TB0777#281-6 (N1mAb)) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0617WJ | Mouse Anti-LRRN1 Recombinant Antibody (clone 2.5.1) | ELISA, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC126 | Recombinant Anti-LRRN1 Vesicular Antibody, EV Displayed (VS-0425-YC126) | ELISA, FC, Cell-uptake |
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