Recombinant Anti-MAG Vesicular Antibody, EV Displayed (VS-0425-YC668) (CAT#: VS-0425-YC668)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• MAG

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Rat

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Myelin associated glycoprotein

• Biological Process
• Cell adhesion

• Cellular Localization
• Equatorial segment, Perinuclear theca

• Introduction
• The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]

• Alternative Names
• GMA, S-MAG, SIGLEC-4A, SIGLEC4A

• Gene ID
• 4099

• UniProt ID
• P20916

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