Recombinant Anti-MAG Vesicular Antibody, EV Displayed (VS-0425-YC668)
CAT#: VS-0425-YC668
The Recombinant Anti-MAG Vesicular Antibody, EV Displayed (VS-0425-YC668) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MAG-expressed cells or tissues. MAG is a myelination protein interacting with sialylated glycoconjugates.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9345/26620_B_9_5.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105695-MAG
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MAG
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Myelin associated glycoprotein
- Biological Process
- Cell adhesion
- Cellular Localization
- Equatorial segment, Perinuclear theca
- Introduction
- The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]
- Alternative Names
- GMA, S-MAG, SIGLEC-4A, SIGLEC4A
- Gene ID
- 4099
- UniProt ID
- P20916
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Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1720CQ | Recombinant Mouse Anti-Mag Antibody (CBL528) | WB, Neut | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-447CQ | Anti-Human MAG Recombinant Antibody (Refanezumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0032-LS-F(E) | Mouse Anti-MAG Recombinant Antibody; Fab Fragment | ELISA | Mouse Fab |
| HPAB-0033-LS-F(E) | Human Anti-MAG Recombinant Antibody (clone BVh1/CVl1); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-J0175-YC-F(E) | Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC); Fab Fragment | ELISA | Mouse Fab |
| HPAB-J0176-YC-F(E) | Human Anti-MAG Recombinant Antibody (clone chAP022/YC); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
| HPAB-J0177-YC-F(E) | Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3); Fab Fragment | ELISA | Humanized (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0032-LS-S(P) | Mouse Anti-MAG Recombinant Antibody; scFv Fragment | ELISA | Mouse scFv |
| HPAB-0033-LS-S(P) | Human Anti-MAG Recombinant Antibody (clone BVh1/CVl1); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-J0175-YC-S(P) | Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC); scFv Fragment | ELISA | Mouse scFv |
| HPAB-J0176-YC-S(P) | Human Anti-MAG Recombinant Antibody (clone chAP022/YC); scFv Fragment | ELISA | Mouse scFv |
| HPAB-J0177-YC-S(P) | Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3); scFv Fragment | ELISA | Humanized (mouse/human) scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-447CQ | Afuco™ Anti-MAG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-447CQ) | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY155 | Human Anti-MAG scFv-Fc Chimera (VS-0425-FY155) | Block | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4168 | Anti-MAG Immunohistochemistry Kit | IHC | |
| VS-0525-XY4169 | Anti-Mouse MAG Immunohistochemistry Kit | IHC |
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