Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3); Fab Fragment (CAT#: HPAB-J0177-YC-F(E))
The product is a Fab fragment targeting myelin associated glycoprotein (MAG). The Fab fragment was made from the mAb BVh3/CVI3. The BVh3/CVI3 promotes oligodendrocyte survival in a human suffering or at risk of developing stroke or another neurological disease.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9345/26620_B_9_5.jpg
(Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9345/26620_B_9_5.jpg
Figure 2 RNA cell line category: Cell line enriched (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105695-MAG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105695-MAG
Figure 2 RNA cell line category: Cell line enriched (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105695-MAG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105695-MAG
Specifications
- Host Species
- Human
- Derivation
- Humanized (mouse/human)
- Type
- Humanized (mouse/human) Fab
- Specificity
- Human MAG
- Species Reactivity
- Human, Rat
- Clone
- BVh3/CVI3
- Applications
- ELISA
- Related Disease
- Neurological diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Myelin Associated Glycoprotein; Sialic Acid Binding Ig-Like Lectin 4A; SIGLEC-4A; GMA; Sialic Acid-Binding Immunoglobulin-Like Lectin 4A; Myelin-Associated Glycoprotein; SIGLEC4A; S-MAG; SPG75
- Gene ID
- 4099
- UniProt ID
- P20916
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1161z | Mouse Anti-MAG Recombinant Antibody (clone 32F9) | WB, IP, IF, IHC, ELISA | Mouse IgG2a, κ |
| HPAB-0032-LS | Human Anti-MAG Recombinant Antibody | ELISA | Chimeric (mouse/human) IgG1, κ |
| HPAB-J0175-YC | Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC) | ELISA | Mouse IgG |
| HPAB-J0176-YC | Human Anti-MAG Recombinant Antibody (clone chAP022/YC) | ELISA | Chimeric (mouse/human) IgG1 |
| HPAB-J0177-YC | Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3) | ELISA, FuncS | Humanized (mouse/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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