Recombinant Anti-MC4R Vesicular Antibody, EV Displayed (VS-0425-YC303)
CAT#: VS-0425-YC303
The Recombinant Anti-MC4R Vesicular Antibody, EV Displayed (VS-0425-YC303) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MC4R-expressed cells or tissues. The MC4R is a melanocortin receptor that is linked to autosomal dominant obesity, acting through G proteins in hormone interactions.
Gene Expression
Normal Tissue
Figure 1 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_9_3.jpg
Normal Tissue
Figure 2 Kidney
Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_8_5.jpg
Normal Tissue
Figure 3 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_6_6.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_7_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (fHDF/TERT166)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166603-MC4R
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MC4R
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Melanocortin 4 receptor
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010]
- Gene ID
- 4160
- UniProt ID
- P32245
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MC4R"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1714-sdAb | Recombinant Anti-Human MC4R VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2008z | Mouse Anti-MC4R Recombinant Antibody (clone 25B11) | WB, ELISA, IF, IP | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
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| TAB-0733CL | Anti-Human MC4R Recombinant Antibody (1E8a) | ICC, IP, WB |
| CAT | Product Name | Application | Type |
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| MOR-2186 | Hi-Affi™ Recombinant Rabbit Anti-MC4R Monoclonal Antibody (DS2186AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC2688 | PE-A*02:01/Human MC4R (SIIDPLIYA) MHC Tetramer | FCM | |
| MHC-LC2694 | PE-A*02:01/Human MC4R (TILIGVFVV) MHC Tetramer | FCM | |
| MHC-LC2930 | APC-A*02:01/Human MC4R (SIIDPLIYA) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY184 | AbPlus™ Anti-MC4R Magnetic Beads (1E8a) | IP, Protein Purification |
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