Recombinant monoclonal antibody 1E8a is a mouse monoclonal antibody that specifically binds to human MC4R and can be potentially used in the treatment of cachexia.
Figure 1 Immunocytochemistry of HEK-293 cells transfected with hMC4R or hMC3R.
The specific membrane labeling was seen in HEK-293 cells expressing hMC4R when incubated with the mAb 1E8a.
Figure 2 The inhibition of hMC4R immunoprecipitation by mAb 1E8a using increasing concentration of the NT peptide.
Results are presented as percentage of inhibition of the
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