Recombinant Mouse Anti-MERTNL Antibody (clone 1F7A6)

CAT#: VS4-CJ34

This mouse anti-MERTNL antibody (clone 1F7A6) is a product that recognizes human MERTNL. The immunogen of this antibody is recombinant human Meteorin-like protein (46aa-311aa). This product was purified by protein A purified and it has been tested for use in ELISA, Immunohistochemistry (1:50-1:200), Flow Cytometry (1:50-1:200).

Specifications

  • Immunogen
  • Recombinant Human Meteorin-like protein (46aa-311aa)
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • Human MERTNL
  • Species Reactivity
  • Human
  • Clone
  • 1F7A6
  • Applications
  • ELISA, IHC, FC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Protein A purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, PBS, pH 7.3.
  • Preservative
  • 0.1% Sodium Azide
  • Storage
  • Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA, Immunohistochemistry (1:50-1:200), Flow Cytometry (1:50-1:200).

Target

  • Alternative Names
  • Meteorin like, glial cell differentiation regulator
  • Long Name
  • Meteorin like, glial cell differentiation regulator
  • Sequence Similarities
  • Belongs to the meteorin family.
  • Cellular Localization
  • Secreted
  • Function
  • Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures (By similarity).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Protocol & Troubleshooting

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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