Recombinant Rabbit Anti-Mouse MMP8 Capture Antibody (clone R11-8H-7) (CAT#: VS3-WK1870)
This antibody is a rabbit recombinant antibody against mouse MMP8. It was developed by immunization of rabbit with recombinant mouse MMP8 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R11-8H-7 and R28-5I-7. The clone R11-8H-7 can be used as a capture antibody in ELISA analysis to identify mouse MMP8.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21763/1984_B2_8_cr5e5901ef3d8ad_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21763/1984_B2_8_cr5e5901ef3d8ad_selected.jpg
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21221/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21221/ihc_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22935/50813_B_6_4.jpg
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22935/50813_B_6_4.jpg
Figure 4 RNA cell line category: Cell line enriched (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118113-MMP8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118113-MMP8
Specifications
- Immunogen
- Recombinant mouse MMP8 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse MMP8
- Species Reactivity
- Mouse
- Clone
- R11-8H-7
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Matrix Metallopeptidase 8; Matrix Metalloproteinase 8 (Neutrophil Collagenase); Matrix Metalloproteinase-8; PMNL Collagenase; PMNL-CL; MMP-8; CLG1
- Gene ID
- 17394
- UniProt ID
- O70138
- Long Name
- Matrix metallopeptidase 8
- Sequence Similarities
- Belongs to the peptidase M10A family.
- Cellular Localization
- Extracellular matrix, Secreted
- Protein Refseq
- NP_032637.3
- Function
- Can degrade fibrillar type I, II, and III collagens. May play a role in the degradation of collagen fibers during uterine involution.
Recommended Products
Detection antibody
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-897-VHH | Recombinant Anti-Mouse Mmp8 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| TAB-0073CL-VHH | Anti-Mouse Mmp8 VHH Single Domain Antibody | ELISA | Single domain antibody |
| TAB-532CL-VHH | Camelid Anti-MMP8 Recombinant Single Domain Antibody (TAB-532CL-VHH) | ELISA, Inhib, FuncS | Camelid VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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