Recombinant Anti-MRC1 Vesicular Antibody, EV Displayed (VS-0425-YC294)
CAT#: VS-0425-YC294
The Recombinant Anti-MRC1 Vesicular Antibody, EV Displayed (VS-0425-YC294) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MRC1-expressed cells or tissues. The MRC1 is a receptor for glycoprotein endocytosis by macrophages, playing roles in pathogen neutralization by recognizing high-mannose structures.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human lung
High expression. RNA expression: 122.3 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4114/155699_A_1_4_selected.jpg
Normal Tissue
Figure 2 IHC staining of human skin
Low expression. RNA expression: 2.8 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4114/155699_B_8_1_val_selected.jpg
Normal Tissue
Figure 3 Colon
Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45134/155703_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45134/155703_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids
Staining: Low
Intensity: Moderate
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4114/155699_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (MOLT-4, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000260314-MRC1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MRC1
- Host Animal
- Human
- Antibody Isotype
- IgG kappa
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Mannose receptor C-type 1
- Biological Process
- Endocytosis, Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Introduction
- The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
- Alternative Names
- bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1
- Gene ID
- 4360
- UniProt ID
- P22897
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC294. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MRC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-672 | Recombinant Anti-human MRC1 Antibody | WB, Neut, FuncS | IgG |
| MHH-672 | Recombinant Human Anti-human MRC1 Antibody | ELISA, WB, Neut, FuncS | IgG |
| MOB-1166CT | Recombinant Mouse anti-Human MRC1 Monoclonal antibody (26-3) | FC, IHC-Fr, WB | |
| MOR-0019-FY | Mouse Anti-MRC1 Recombinant Antibody (clone 15-2) | FC, FuncS, WB | Mouse IgG1 |
| VS3-FY260 | Recombinant Mouse Anti-MRC1 Antibody (clone 4B11C12) | ELISA, FC, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-672-F(E) | Recombinant Anti-human MRC1 Antibody Fab Fragment | RIA, ELISA, FuncS | Fab |
| MHH-672-F(E) | Recombinant Human Anti-human MRC1 Antibody Fab Fragment | WB, ELISA, IHC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-672-S(P) | Recombinant Anti-human MRC1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| MHH-672-S(P) | Recombinant Human Anti-human MRC1 Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-007 | Recombinant Anti-human MRC1 VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
| TAB-0074CL-VHH | Anti-Human MRC1 VHH Single Domain Antibody (TAB-0074CL-VHH) | ELISA | Single domain antibody |
| HPAB-0924WJ | Recombinant Camelid Anti-MRC1 Single Domain Antibody | ELISA, PP, SPR, FC | Camelid VHH |
| DAB-123YJL | Camelid Anti-MRC1 Recombinant Antibody (DAB-123YJL) | ELISA, SPR, FC, RIA | Camelid VHH |
| DAB-128YJL | Camelid Anti-MRC1 Recombinant Antibody (DAB-128YJL) | ELISA, SPR, FC, RIA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0828CL | Anti-Human MRC1 Recombinant Antibody (B11) | ELISA | Human antibody |
| TAB-0828CL-S(P) | Anti-Human MRC1 Recombinant Antibody scFv Fragment (B11) | ELISA | Human antibody |
| TAB-0828CL-F(E) | Anti-Human MRC1 Recombinant Antibody Fab Fragment (B11) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2280 | Hi-Affi™ Recombinant Rabbit Anti-MRC1 Monoclonal Antibody (DS2280AB) | WB, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY167 | CytoStream™ Mouse Anti-MRC1 Recombinant Antibody (clone 15-2) | FC | Mouse IgG1, kappa |
| VS13-YC739 | CytoStream™ Rat Anti-Mouse Mrc1 Recombinant Antibody (VS13-YC739) | FC | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4488 | Anti-MRC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4489 | Anti-Human MRC1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: FuncS, Inhib, IP, ELISA
Application: Neut, Inhib, FC, ELISA
-YJ5.png)
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, FC
Application: SPR, Inhib, FuncS
Application: FC, IHC, Cyt, FuncS
Application: Neut, IHC, Activ, FuncS, IF, ELISA
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
