Recombinant Anti-MRC1 Vesicular Antibody, EV Displayed (VS-0425-YC294) (CAT#: VS-0425-YC294)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• MRC1

• Host Animal
• Human

• Antibody Isotype
• IgG kappa

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Mannose receptor C-type 1

• Biological Process
• Endocytosis, Host-virus interaction

• Molecular Function
• Host cell receptor for virus entry, Receptor

• Introduction
• The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

• Alternative Names
• bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1

• Gene ID
• 4360

• UniProt ID
• P22897

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