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MRE11
Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9)

Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9) (CAT#: VS3-FY952)

Name: Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9)
SKU: VS3-FY952
Rating: 5 (1 reviews)

This product is a recombinant rabbit antibody that recognizes MRE11. This antibody has been reported for use in Western Blot, Immunohistochemistry-Paraffin. The clone R03-6H9 is specific for human, mouse, rat MRE11. The antigen is human mre11 recombinant protein.

Tested Data
Gene Expression
Datasheet
MSDS
COA

Figure 1. Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9) in WB.

Figure 1. Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9) in WB.

Western Blot analysis of Mre11 in K562, rat brain, C6, 3T3, Hela lysates using Mre11 Antibody.

IHC-P

Figure 2. Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9) in IHC-P.

Figure 2. Recombinant Rabbit Anti-MRE11 Antibody (clone R03-6H9) in IHC-P.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Mre11 antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.

Subcellular Location

Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/if_selected.jpg

Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4081/if_selected.jpg

Normal Tissue

Figure 3 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/7879_A_7_8.jpg

Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/7879_B_7_5.jpg

Figure 5 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/7879_A_8_3.jpg

Figure 6 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: nuclear Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/7879_A_7_4.jpg

Figure 7 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/7879_A_8_5.jpg

Figure 8 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2691/7879_A_4_6.jpg

RNA Expression

Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000020922-MRE11

Datasheet

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
Human Mre11 recombinant protein.

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human, Mouse, Rat MRE11

Species Reactivity
Human, Mouse, Rat

Clone
R03-6H9

Applications
Western Blot, Immunohistochemistry-Paraffin

Conjugate
Unconjugated

MW
Calculated MW: 81 kDa; Observed MW: 81 kDa

Product Property

Purification
Affinity Purified

Purity
>95% as determined by SDS-PAGE

Buffer
50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA

Preservative
0.01% Sodium azide

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
Western Blot: 1/500-1/1000
Immunohistochemistry-Paraffin: 1/50-1/100

Target

Alternative Names
MRE11 Homolog, Double Strand Break Repair Nuclease; MRE11 Homolog A, Double Strand Break Repair Nuclease; Double-Strand Break Repair Protein MRE11A; Meiotic Recombination 11 Homolog 1; Meiotic Recombination 11 Homolog A; AT-Like Disease; MRE11 Homolog 1; MRE11A; HNGS1; MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae); MRE11 Homolog, Double Strand Break Repair Nuclease A

Gene ID
4361

UniProt ID
P49959

Secondary Antibody

Isotype Control

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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IgG Antibody Products Antibody Magnetic Beads

CAT	Product Name	Application	Type
MRO-1023-CN	Recombinant Rabbit Anti-MRE11 Monoclonal Antibody (JM11-18)	WB, IHC	Rabbit IgG
VS3-WK559	Rabbit Anti-MRE11 Recombinant Antibody (clone JM11-18)	WB, IHC	Rabbit IgG
VS3-FY950	Recombinant Mouse Anti-MRE11 Antibody (clone 4D2B6)	ELISA, IHC, FC	Mouse IgG1
VS3-FY951	Recombinant Mouse Anti-MRE11 Antibody (clone 7C8A9)	ELISA, WB, IHC, FC	Mouse IgG2b

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