Recombinant Anti-NCR1 Vesicular Antibody, EV Displayed (VS-0425-YC353)
CAT#: VS-0425-YC353
The Recombinant Anti-NCR1 Vesicular Antibody, EV Displayed (VS-0425-YC353) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to NCR1-expressed cells or tissues. The NCR1 is a receptor that enhances NK cell-mediated tumor lysis, contributing to immune cell efficiency.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49311/1524_G9_2_selected.jpg
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Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- NCR1
- Host Animal
- Human
- Antibody Isotype
- IgG4
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 1.84 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Natural cytotoxicity triggering receptor 1
- Molecular Function
- Receptor
- Introduction
- Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
- Alternative Names
- CD335, LY94, NK-p46, NKP46
- Gene ID
- 9437
- UniProt ID
- O76036
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
| MOB-3142z | Mouse Anti-NCR1 Recombinant Antibody (clone 37H3) | WB, FC, IHC, IHC | Mouse IgG2 |
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| VS11-QX116 | Human Anti-NCR1 Recombinant Antibody (clone Bab281) | FC, IP, IF | Human IgG1, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0223CL | Anti-Human NCR1 Recombinant Antibody | Block, FuncS, Neut | Chimeric |
| TAB-0223CL-S(P) | Anti-Human NCR1 Recombinant Antibody scFv Fragment | Block, FuncS, Neut | Chimeric |
| TAB-0223CL-F(E) | Anti-Human NCR1 Recombinant Antibody Fab Fragment | Block, FuncS, Neut | Chimeric |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY36 | Mouse Anti-NCR1 Agonistic Antibody (VS-0724-XY36) | WB, FC, IHC, Agonistic assays, CyTOF®, ICC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY34 | Human Anti-NCR1 scFv-Fc Chimera (VS-0325-FY34) | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4717 | Anti-NCR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4718 | Anti-Mouse NCR1 Immunohistochemistry Kit | IHC |
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