Recombinant Anti-NCR1 Vesicular Antibody, EV Displayed (VS-0425-YC353) (CAT#: VS-0425-YC353)
The Recombinant Anti-NCR1 Vesicular Antibody, EV Displayed (VS-0425-YC353) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to NCR1-expressed cells or tissues. The NCR1 is a receptor that enhances NK cell-mediated tumor lysis, contributing to immune cell efficiency.
Specific Inquiry
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49311/1524_G9_2_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49311/1524_G9_2_selected.jpg
Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- NCR1
- Host Animal
- Human
- Antibody Isotype
- IgG4
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 1.84 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Natural cytotoxicity triggering receptor 1
- Molecular Function
- Receptor
- Introduction
- Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
- Alternative Names
- CD335, LY94, NK-p46, NKP46
- Gene ID
- 9437
- UniProt ID
- O76036
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3142z | Mouse Anti-NCR1 Recombinant Antibody (clone 37H3) | WB, FC, IHC, IHC | Mouse IgG2 |
| MOB-1307MZ | Recombinant Mouse Anti-Human NCR1 Antibody (clone NN0502-9G35) | FC, IHC-Fr, WB | Mouse antibody |
| MOB-077YJL | Rat Anti-NCR1 Recombinant Antibody (clone 29A1.4) | ELISA, FC | Rat IgG2a |
| VS11-QX116 | Human Anti-NCR1 Recombinant Antibody (clone Bab281) | FC, IP, IF | Human IgG1, κ |
| VS13-YC773 | Rabbit Anti-NCR1 Recombinant Antibody (VS13-YC773) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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