Recombinant Mouse Anti-NOS2 Antibody (clone 2H6B10)
CAT#: VS4-CJ56
This mouse anti-NOS2 antibody (clone 2H6B10) is a product that recognizes human NOS2. The immunogen of this antibody is recombinant human Nitric oxide synthase, inducible protein (1aa-200aa). This product was purified by protein G purified and it has been tested for use in ELISA, Western Blot (1:1000-1:5000), Flow Cytometry (1:50-1:200).
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2014/166726_B_8_5.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2014/166726_A_9_4.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (CACO-2, SCLC-21H)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000007171-NOS2
❮
❯
Specifications
- Immunogen
- Recombinant Human Nitric oxide synthase, inducible protein (1aa-200aa)
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human NOS2
- Species Reactivity
- Human
- Clone
- 2H6B10
- Applications
- ELISA, WB, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, PBS, pH 7.3.
- Preservative
- 0.1% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot (1:1000-1:5000), Flow Cytometry (1:50-1:200).
Target
- Alternative Names
- NOS; INOS; NOS2A; HEP-NOS
- Gene ID
- 4843
- UniProt ID
- P35228
- Long Name
- Nitric oxide synthase 2
- Sequence Similarities
- Belongs to the NOS family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Polyubiquitinated; mediated by SPSB1, SPSB2 and SPSB4, leading to proteasomal degradation.
- Protein Refseq
- NP_000616.3
- Function
- Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004, PubMed:7682706, PubMed:7504305).
In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).
As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112).
Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8 (PubMed:19688109).
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS4-CJ56. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
AGE-RAGE Signaling Pathway in Diabetic Complications
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "NOS2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1473z | Mouse Anti-NOS2 Recombinant Antibody (clone 26B5) | WB, ELISA, FC, IF, IHC, IP | Mouse IgG1, κ |
| MOB-2264MZ | Recombinant Mouse Anti-Mouse NOS2 Antibody (clone OPT-JO) | ICC, IF, WB | Mouse antibody |
| MRO-1976-CN | Rabbit Anti-NOS2 Polyclonal Antibody (MRO-1976-CN) | IF, IHC, FC, WB | Rabbit IgG |
| VS3-XY1171 | Mouse Anti-NOS2 Recombinant Antibody (clone 4E5) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-XY3449 | Rabbit Anti-NOS2 Recombinant Antibody (clone R05-6G2) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2472 | Hi-Affi™ Recombinant Rabbit Anti-NOS2 Monoclonal Antibody (DS2472AB) | IHC-P, IHC-Fr | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-044CN | Human Anti-NOS2 Recombinant Antibody (clone 1E8-B8) | ELISA, FC | Human IgG1, κ |
| NS-045CN | Human Anti-NOS2 Recombinant Antibody (clone 2D10-2H9) | ELISA, FC | Human IgG2a, κ |
| NS-046CN | Human Anti-NOS2 Recombinant Antibody (clone 24H9-1F3) | ELISA, FC | Chimeric (mouse/human) IgG1, κ |
| NS-046CN-F(E) | Human Anti-NOS2 Recombinant Antibody (clone 24H9-1F3); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| NS-046CN-S(P) | Mouse Anti-NOS2 Recombinant Antibody (clone 24H9-1F3); scFv Fragment | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-044CN-F(E) | Human Anti-NOS2 Recombinant Antibody (clone 1E8-B8); Fab Fragment | ELISA, FC | Human Fab |
| NS-045CN-F(E) | Human Anti-NOS2 Recombinant Antibody (clone 2D10-2H9); Fab Fragment | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-044CN-S(P) | Human Anti-NOS2 Recombinant Antibody (clone 1E8-B8); scFv Fragment | ELISA, FC | Human scFv |
| NS-045CN-S(P) | Human Anti-NOS2 Recombinant Antibody (clone 2D10-2H9); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4900 | Anti-NOS2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4901 | Anti-Mouse NOS2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4902 | Anti-Bovine NOS2 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: Neut, Inhib, FC, ELISA
Application: ELISA, Inhib, FC
Application: ELISA, Neut
Application: ELISA, FC, IHC, Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
