Recombinant Anti-NPR2 Vesicular Antibody, EV Displayed (VS-0425-YC38)
CAT#: VS-0425-YC38
The Recombinant Anti-NPR2 Vesicular Antibody, EV Displayed (VS-0425-YC38) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to NPR2-expressed cells or tissues. The NPR2 is a receptor important for natriuretic peptide activity and linked to disorders like acromesomelic dysplasia.
Gene Expression
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, JURKAT, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000159899-NPR2
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- NPR2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Natriuretic peptide receptor 2
- Biological Process
- cGMP biosynthesis, Osteogenesis
- Molecular Function
- Lyase, Receptor
- Introduction
- This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
- Alternative Names
- AMDM, ANPb, ANPRB, GC-B, GUCY2B, NPRB
- Gene ID
- 4882
- UniProt ID
- P20594
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Datasheet
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See other products for "NPR2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1281z | Mouse Anti-NPR2 Recombinant Antibody (clone 3G2) | ELISA, IHC, WB | Mouse IgG2b, κ |
| MOB-0020CT | Recombinant Mouse anti-Human NPR2 Monoclonal antibody (EML696) | IHC-P, WB | |
| VS-0224-XY98 | Mouse Anti-NPR2 Recombinant Antibody (VS-0224-XY98) | ELISA, WB, IHC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2484 | Hi-Affi™ Recombinant Rabbit Anti-NPR2 Monoclonal Antibody (DS2484AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4929 | Anti-NPR2 Immunohistochemistry Kit | IHC |
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