Recombinant Anti-OLR1 Vesicular Antibody, EV Displayed (VS-0425-YC309) (CAT#: VS-0425-YC309)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• OLR1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Macaque

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Oxidized low density lipoprotein receptor 1

• Biological Process
• Cell adhesion, Immunity, Inflammatory response

• Molecular Function
• Receptor

• Cellular Localization
• Nucleoplasm, Plasma membrane, Vesicles

• Introduction
• This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

• Alternative Names
• CLEC8A, LOX-1, SCARE1

• Gene ID
• 4973

• UniProt ID
• P78380

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