Chicken Anti-OLR1 Recombinant Antibody (clone HUC3-48)
CAT#: HPAB-0072-LS
The antibody has high efficiency in action and excellent cross-reactivity, playing a critical role in particular for the diagnosis, prevention or treatment of diseases associated with biological defense and inflammatory diseases.
Published Data
Gene Expression
ELISA
Figure 1 The results of a) measurement of the binding state of a recombinant chicken antibody to recombinant LOX-1, and b) the cross-reactivity of nine recombinant chicken antibodies against LOX-1 from four species using ELISA.
Inhib
Figure 2 The measurement results of the inhibition ratios of oxLDL and LOX-1 with a recombinant chicken antibody and a chicken-human chimeric antibody, respectively.
FC
Figure 3 The binding state of chicken-human chimeric antibody to CHO cells expressing LOX-1.
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Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50798/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (CACO-2, HaCaT, HHSteC, hTCEpi, SiHa, SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173391-OLR1
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Specifications
- Immunogen
- OLR1
- Host Species
- Chicken
- Derivation
- Chicken
- Type
- Chicken IgY
- Species Reactivity
- Human, Mouse
- Clone
- HUC3-48
- Applications
- ELISA, FC, Inhib
- Related Disease
- Thrombosis, Thrombocytopenia
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry, Inhibition.
Target
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Efficient OLR1 Inhibition
We used this chicken recombinant antibody to inhibit the function of OLR1 in our cell culture model. It demonstrated high efficiency in blocking the receptor, helping us understand the role of OLR1 in inflammatory signaling pathways.
High Purity Chicken IgY
The quality of this antibody is top-notch, with purity greater than 95 percent. Since it is a chicken IgY, it was perfect for our double-staining experiments involving mammalian primary antibodies, as it avoided cross-species secondary antibody issues.
Q&As
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Can this antibody be used for Flow Cytometry?
A: Yes, this Chicken Anti-OLR1 Recombinant Antibody (clone HUC3-48) has been tested and is suitable for use in Flow Cytometry (FC), as well as Enzyme-linked Immunosorbent Assay (ELISA) and Inhibition studies.
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What species does this antibody react with?
A: This antibody demonstrates excellent cross-reactivity and is capable of binding to OLR1 from both Human and Mouse species. It plays a critical role in research related to biological defense and inflammatory diseases.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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- CAT
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| CAT | Product Name | Application | Type |
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| HPAB-0072-LS-F(E) | Chicken Anti-OLR1 Recombinant Antibody (clone HUC3-48); Fab Fragment | Inhib, ELISA | Chicken Fab |
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