Recombinant Rabbit Anti-RAB27A Antibody (clone 2E8) (CAT#: VS4-CJ100)
This rabbit anti-RAB27A antibody (clone 2E8) is a product that recognizes human RAB27A. The immunogen of this antibody is a synthesized peptide derived from human RAB27A. The mAb has been tested for use in ELISA, Flow Cytometry (1:50-1:200).
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Normal Tissue
RNA Expression
Figure 1 Stomach 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1333/4092_A_5_1_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1333/4092_A_5_1_val_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34046/86912_B_9_5.jpg
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34046/86912_B_9_5.jpg
Figure 3 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34046/85405_A_9_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34046/85405_A_9_3.jpg
Figure 4 RNA cell line category: Cell line enhanced (HL-60, K-562, Karpas-707, SK-MEL-30, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000069974-RAB27A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000069974-RAB27A
Specifications
- Immunogen
- A synthesized peptide derived from human RAB27A
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human RAB27A
- Species Reactivity
- Human
- Clone
- 2E8
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry (1:50-1:200).
Target
- Alternative Names
- GS2; RAM; RAB27; HsT18676
- Gene ID
- 5873
- UniProt ID
- P51159
- Long Name
- RAB27A, member RAS oncogene family
- Sequence Similarities
- Belongs to the small GTPase superfamily. Rab family.
- Cellular Localization
- Endosome, Lysosome, Membrane
- Protein Refseq
- NP_004571.2; NP_899057.1; NP_899058.1
- Function
- Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381).
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
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| MOB-1745CT | Recombinant Mouse anti-Human RAB27A Monoclonal antibody (EML672) | ICC/IF, IHC-FoFr, IHC-P, IP, WB | |
| VS3-QX944 | Mouse Anti-RAB27A Recombinant Antibody (clone 9D-7C) | WB, IHC | Mouse IgG2b |
| VS3-CJ1016 | Mouse Anti-RAB27A Recombinant Antibody (VS3-CJ1016) | WB, FC | Mouse IgG1, κ |
| VS3-XY1349 | Mouse Anti-RAB27A Recombinant Antibody (clone 7D7C9) | IHC | Mouse IgG2b |
| VS3-FY2853 | Mouse Anti-RAB27A Recombinant Antibody (VS3-FY2853) | WB, FC | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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