Recombinant Rabbit Anti-RAB27A Antibody (clone 2E8)

CAT#: VS4-CJ100

This rabbit anti-RAB27A antibody (clone 2E8) is a product that recognizes human RAB27A. The immunogen of this antibody is a synthesized peptide derived from human RAB27A. The mAb has been tested for use in ELISA, Flow Cytometry (1:50-1:200).

Gene Expression
Figure 1 Stomach 1 Figure 2 Cerebral cortex Figure 3 Colon Figure 4 RNA cell line category: Cell line enhanced (HL-60, K-562, Karpas-707, SK-MEL-30, U-937)

Specifications

  • Immunogen
  • A synthesized peptide derived from human RAB27A
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human RAB27A
  • Species Reactivity
  • Human
  • Clone
  • 2E8
  • Applications
  • ELISA, FC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.
  • Preservative
  • 0.02% Sodium Azide
  • Storage
  • Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA, Flow Cytometry (1:50-1:200).

Target

  • Alternative Names
  • GS2; RAM; RAB27; HsT18676
  • Long Name
  • RAB27A, member RAS oncogene family
  • Sequence Similarities
  • Belongs to the small GTPase superfamily. Rab family.
  • Cellular Localization
  • Endosome, Lysosome, Membrane
  • Function
  • Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381).
    Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Secondary Antibody

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MOR-2960 Hi-Affi™ Recombinant Rabbit Anti-RAB27A Monoclonal Antibody (DS2960AB) WB, IHC, ICC, IP, FC IgG
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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