Recombinant Anti-RGMB Vesicular Antibody, EV Displayed (VS-0425-YC604)
CAT#: VS-0425-YC604
The Recombinant Anti-RGMB Vesicular Antibody, EV Displayed (VS-0425-YC604) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RGMB-expressed cells or tissues. RGMB is a GPI-anchored protein member of the repulsive guidance molecule family, contributing to nervous system patterning.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16993/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HBF TERT88, LHCN-M2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174136-RGMB
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Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- RGMB
- Host Animal
- Rat
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Repulsive guidance molecule BMP co-receptor b
- Cellular Localization
- Nucleoplasm
- Introduction
- RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]
- Alternative Names
- DRAGON, FLJ90406
- Gene ID
- 285704
- UniProt ID
- Q6NW40
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Related Signaling Pathways
TGF-β Signaling Pathway
Downloadable Resources
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Datasheet
MSDS
COA
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See other products for "RGMB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0222-YJ | Rat Anti-RGMB Recombinant Antibody (HPAB-0222-YJ) | ELISA, FC, Block, IF, FuncS | Rat IgG, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0222-YJ-S(P) | Rat Anti-RGMB Recombinant Antibody; scFv Fragment (HPAB-0222-YJ-S(P)) | ELISA, Block, FC, IF, Inhib | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0222-YJ-F(E) | Rat Anti-RGMB Recombinant Antibody; Fab Fragment (HPAB-0222-YJ-F(E)) | ELISA, Block, FC, IF, Inhib | Rat Fab |
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