Recombinant Anti-RGMB Vesicular Antibody, EV Displayed (VS-0425-YC604) (CAT#: VS-0425-YC604)
The Recombinant Anti-RGMB Vesicular Antibody, EV Displayed (VS-0425-YC604) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RGMB-expressed cells or tissues. RGMB is a GPI-anchored protein member of the repulsive guidance molecule family, contributing to nervous system patterning.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16993/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16993/if_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HBF TERT88, LHCN-M2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174136-RGMB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174136-RGMB
Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- RGMB
- Host Animal
- Rat
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Repulsive guidance molecule BMP co-receptor b
- Cellular Localization
- Nucleoplasm
- Introduction
- RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]
- Alternative Names
- DRAGON, FLJ90406
- Gene ID
- 285704
- UniProt ID
- Q6NW40
Related Resources
TGF-β Signaling Pathway
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0222-YJ | Rat Anti-RGMB Recombinant Antibody (HPAB-0222-YJ) | ELISA, FC, Block, IF, FuncS | Rat IgG, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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