Recombinant Anti-RTN4R Vesicular Antibody, EV Displayed (VS-0425-YC128) (CAT#: VS-0425-YC128)
The Recombinant Anti-RTN4R Vesicular Antibody, EV Displayed (VS-0425-YC128) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RTN4R-expressed cells or tissues. The RTN4R is the receptor for reticulon 4, mediating axonal growth inhibition, influencing axonal regeneration, and plasticity in the central nervous system.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (NB-4, REH, SCLC-21H, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- RTN4R
- Host Animal
- Mouse
- Antibody Isotype
- IgG2a kappa
- Species Reactivity
- Human, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Reticulon 4 receptor
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Focal adhesion sites, Actin filaments
- Introduction
- This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
- Alternative Names
- NOGOR
- Gene ID
- 65078
- UniProt ID
- Q9BZR6
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|---|---|---|---|
| MOB-869 | Recombinant Anti-human RTN4R Antibody | WB, ELISA, IHC, FuncS | IgG |
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| PABL-695 | Mouse Anti-RTN4R Recombinant Antibody (clone 1D9) | ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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