Recombinant Anti-RTN4R Vesicular Antibody, EV Displayed (VS-0425-YC128)
CAT#: VS-0425-YC128
The Recombinant Anti-RTN4R Vesicular Antibody, EV Displayed (VS-0425-YC128) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RTN4R-expressed cells or tissues. The RTN4R is the receptor for reticulon 4, mediating axonal growth inhibition, influencing axonal regeneration, and plasticity in the central nervous system.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (NB-4, REH, SCLC-21H, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- RTN4R
- Host Animal
- Mouse
- Antibody Isotype
- IgG2a kappa
- Species Reactivity
- Human, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Reticulon 4 receptor
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Focal adhesion sites, Actin filaments
- Introduction
- This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
- Alternative Names
- NOGOR
- Gene ID
- 65078
- UniProt ID
- Q9BZR6
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Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| MOB-869-F(E) | Recombinant Anti-human RTN4R Antibody Fab Fragment | FC, WB, FuncS | Fab |
| MHH-869-F(E) | Recombinant Human Anti-human RTN4R Antibody Fab Fragment | WB, IP, FuncS | Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-869-S(P) | Recombinant Anti-human RTN4R Antibody scFv Fragment | WB, IP, FuncS | scFv |
| MHH-869-S(P) | Recombinant Human Anti-human RTN4R Antibody scFv Fragment | ELISA, WB, Neut, FuncS | scFv |
| PSBL-688 | Mouse Anti-RTN4R Recombinant Antibody (clone 1D9); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0738-YJ-S(P) | Rabbit Anti-RTN4R Recombinant Antibody (M5); scFv Fragment | ELISA, FC, WB, ICC, IF | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-515MZ | Mouse Anti-RTN4R Recombinant Antibody (TAB-515MZ) | ELISA, FC | Mouse IgG2a, κ |
| TAB-516MZ | Mouse Anti-RTN4R Recombinant Antibody (TAB-516MZ) | FC, FuncS, Neut | Mouse IgG2a, κ |
| TAB-515MZ-S(P) | Mouse Anti-RTN4R Recombinant Antibody; scFv Fragment (TAB-515MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-516MZ-S(P) | Mouse Anti-RTN4R Recombinant Antibody; scFv Fragment (TAB-516MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-515MZ-F(E) | Mouse Anti-RTN4R Recombinant Antibody; Fab Fragment (TAB-515MZ-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-523MZ | Human Anti-RTN4R Recombinant Antibody (TAB-523MZ) | ELISA | Human antibody |
| TAB-524MZ | Human Anti-RTN4R Recombinant Antibody (TAB-524MZ) | ELISA | Human antibody |
| TAB-523MZ-S(P) | Human Anti-RTN4R Recombinant Antibody; scFv Fragment (TAB-523MZ-S(P)) | ELISA | Human scFv |
| TAB-524MZ-S(P) | Human Anti-RTN4R Recombinant Antibody; scFv Fragment (TAB-524MZ-S(P)) | ELISA | Human scFv |
| TAB-525MZ-S(P) | Human Anti-RTN4R Recombinant Antibody; scFv Fragment (TAB-525MZ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| NS-052CN-F(E) | Human Anti-RTN4R Recombinant Antibody (clone CBL04Q); Fab Fragment | ELISA, WB, IHC | Humanized Fab |
| NS-059CN-F(E) | Human Anti-RTN4R Recombinant Antibody; Fab Fragment (NS-059CN-F(E)) | ELISA, WB | Human Fab |
| NS-052CN-S(P) | Human Anti-RTN4R Recombinant Antibody (clone CBL04Q); scFv Fragment | ELISA, WB, IHC | Humanized scFv |
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