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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes
Membrane
Cell type enhanced (Excitatory neurons, Bipolar cells, Muller glia cells)
Immune cell enhanced (MAIT T-cell)
Cell line enhanced (NB-4, REH, SCLC-21H, SK-MEL-30)
Homodimer (PubMed:18411262). Interacts with MAG (PubMed:12089450, 12839991, 18411262, 19052207). Interacts with RTN4 (PubMed:12839991, 19052207). Interacts with NGFR (PubMed:12426574, 18411262, 19052207). Interacts with LINGO1 (PubMed:14966521, 19052207). Interacts with KIAA0319L (PubMed:20697954). Interacts with OLFM1; this inhibits interaction with LINGO1 and NGFR (By similarity). Interacts with OMG (PubMed:12068310, 12839991, 19052207).
Receptor