Recombinant Human Anti-human RTN4R Antibody (CAT#: MHH-869)
Recombinant Human Antibody shows strong binding capacity to Human RTN4R, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-RTN4R mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-RTN4R mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (NB-4, REH, SCLC-21H, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
Specifications
- Immunogen
- Human reticulon 4 receptor
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human reticulon 4 receptor
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Immunofluorescence; Western blot; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- RTN4R; reticulon 4 receptor; NGR; NOGOR; reticulon-4 receptor; UNQ330/PRO526; nogo receptor; Nogo-66 receptor
- Gene ID
- 65078
- UniProt ID
- Q9BZR6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-869 | Recombinant Anti-human RTN4R Antibody | WB, ELISA, IHC, FuncS | IgG |
| PABL-695 | Mouse Anti-RTN4R Recombinant Antibody (clone 1D9) | ELISA | Mouse IgG1 |
| HPAB-0738-YJ | Human Anti-RTN4R Recombinant Antibody (M5) | ELISA, WB, FC, IF, IP, ICC | Chimeric (rabbit/human) IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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