Recombinant Anti-SCARB1 Vesicular Antibody, EV Displayed (VS-0425-YC516)
CAT#: VS-0425-YC516
The Recombinant Anti-SCARB1 Vesicular Antibody, EV Displayed (VS-0425-YC516) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SCARB1-expressed cells or tissues. SCARB1 is a protein that serves as a plasma membrane receptor for high-density lipoprotein cholesterol (HDL). The protein facilitates cholesterol transfer to and from HDL and is also a receptor for hepatitis C virus glycoprotein E2.





Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SCARB1
- Host Animal
- Human
- Antibody Isotype
- IgG4
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 1.84 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Scavenger receptor class B member 1
- Biological Process
- Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Cellular Localization
- Vesicles, Lysosomes, Rods & Rings
- Introduction
- The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
- Alternative Names
- CD36L1, CLA-1, CLA1, SR-BI, SRB1
- Gene ID
- 949
- UniProt ID
- Q8WTV0
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Datasheet
MSDS
COA
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