Human Anti-SCARB1 Recombinant Antibody (clone scFVC11) (CAT#: HPAB-0298CQ)
This product is a recombinant human antibody that recognizes SCARB1. The antibody binds to a SR-BI target region involved in HCV E2 binding. scFVC11 can block HCV infection of cultured human hepatocytes.
Specific Inquiry
Inhib
Figure 1 The inhibition of HCV infection of cultured human hepatocytes by the single-chain antibody scFVC11.
Viral replication was measured on total RNA by quantitative PCR and expressed as number of HCV copies/350000 cells. The experiment was performed in triplicate wells and values are shown with standard deviations. Single-chain antibody was tested at two different concentrations: 25 and 5 μg/ml. As a control, an unrelated single-chain antibody was used (FV) at the concentration of 25 μg/ml. As a positive control of inhibition of infection, a HCV replicase inhibitor was used ("Pol inhibitor").
Specifications
- Immunogen
- Human SR-B1 receptor
- Host Species
- Human
- Type
- Human IgG4, λ
- Specificity
- Human SCARB1
- Species Reactivity
- Human
- Clone
- scFVC11
- Applications
- ELISA, Inhib, FC, Cyt, ADCC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, Flow Cytometry, Cytotoxicity and Antibody-dependent Cellular Cytotoxicityotoxicity Assay. Please see the Published Data for further information.
Target
- Alternative Names
- Scavenger Receptor Class B Member 1; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 1; CD36 And LIMPII Analogous 1; CD36L1; CLA-1; SR-BI; CLA1; SRB1;
- Gene ID
- 949
- UniProt ID
- Q8WTV0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone scFVC11"
See other products for "SCARB1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1865z | Mouse Anti-SCARB1 Recombinant Antibody (clone 4H1) | WB, ICC, IF, IHC | Mouse IgG1 |
| MOB-1397CT | Recombinant Mouse anti-Rat SCARB1 Monoclonal antibody (4E23) | FC, IHC-Fr, Neut | |
| MRO-1368-CN | Recombinant Rabbit Anti-SCARB1 Monoclonal Antibody (CBACN-496) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-1609-FY | Recombinant Human Anti-SCARB1 Antibody (mAb8) | Inhib, Neut, FC | Human IgG4 |
| HPAB-1610-FY | Recombinant Human Anti-SCARB1 Antibody (mAb81) | Inhib, FC | Human IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1927CQ | Recombinant Mouse Anti-Scarb1 Antibody (CBL917) | FC, IHC, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3179 | Hi-Affi™ Recombinant Rabbit Anti-SCARB1 Monoclonal Antibody (DS3179AB) | WB, IHC, ICC | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0384-CN-S(P) | Mouse Anti-SCARB1 Recombinant Antibody; scFv Fragment (HPAB-0384-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0298CQ-S(P) | Human Anti-SCARB1 Recombinant Antibody (clone scFVC11); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-1609-FY-F(E) | Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb8) | Inhib, ELISA, FC | Human scFv |
| HPAB-1610-FY-F(E) | Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb81) | Inhib, ELISA | Human scFv |
| HPAB-1611-FY-F(E) | Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb15) | Inhib, ELISA, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0384-CN-F(E) | Mouse Anti-SCARB1 Recombinant Antibody; Fab Fragment (HPAB-0384-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0298CQ-F(E) | Human Anti-SCARB1 Recombinant Antibody (clone scFVC11); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-1609-FY-S(P) | Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb8) | Inhib, ELISA, FC | Human Fab |
| HPAB-1610-FY-S(P) | Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb81) | Inhib, ELISA | Human Fab |
| HPAB-1611-FY-S(P) | Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb15) | Inhib, ELISA, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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