Human Anti-SCARB1 Recombinant Antibody (clone scFVC11) (CAT#: HPAB-0298CQ)
This product is a recombinant human antibody that recognizes SCARB1. The antibody binds to a SR-BI target region involved in HCV E2 binding. scFVC11 can block HCV infection of cultured human hepatocytes.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 The inhibition of HCV infection of cultured human hepatocytes by the single-chain antibody scFVC11.
Viral replication was measured on total RNA by quantitative PCR and expressed as number of HCV copies/350000 cells. The experiment was performed in triplicate wells and values are shown with standard deviations. Single-chain antibody was tested at two different concentrations: 25 and 5 μg/ml. As a control, an unrelated single-chain antibody was used (FV) at the concentration of 25 μg/ml. As a positive control of inhibition of infection, a HCV replicase inhibitor was used ("Pol inhibitor").
Specifications
- Immunogen
- Human SR-B1 receptor
- Host Species
- Human
- Type
- Human IgG4, λ
- Specificity
- Human SCARB1
- Species Reactivity
- Human
- Clone
- scFVC11
- Applications
- ELISA, Inhib, FC, Cyt, ADCC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, Flow Cytometry, Cytotoxicity and Antibody-dependent Cellular Cytotoxicityotoxicity Assay. Please see the Published Data for further information.
Target
- Alternative Names
- Scavenger Receptor Class B Member 1; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 1; CD36 And LIMPII Analogous 1; CD36L1; CLA-1; SR-BI; CLA1; SRB1;
- Gene ID
- 949
- UniProt ID
- Q8WTV0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1927CQ | Recombinant Mouse Anti-Scarb1 Antibody (CBL917) | FC, IHC, Neut | IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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