Recombinant Anti-SEZ6 Vesicular Antibody, EV Displayed (VS-0425-YC153) (CAT#: VS-0425-YC153)
The Recombinant Anti-SEZ6 Vesicular Antibody, EV Displayed (VS-0425-YC153) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SEZ6-expressed cells or tissues. The SEZ6 is a protein associated with febrile seizures, containing domains similar to sushi and CUB domains.

(Glial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11777/28621_B_7_5.jpg

(GLUC cells - cytoplasm/membrane
Staining:High
Intensity: Strong
Molecular layer cells - cytoplasm/membrane
Staining:High
Intensity: Strong
Processes in granular layer
Staining:Medium
Intensity: Moderate
Processes in white matter
Staining:Medium
Intensity: Moderate
Purkinje cells - cytoplasm/membrane
Staining:High
Intensity: Strong
Purkinje cells - dendrites
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11777/28621_B_9_8.jpg

(Enterocytes - Microvilli
Staining:Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11777/28621_A_9_3.jpg

(Proximal tubules (cell body)
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11777/28621_A_7_5.jpg

(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11777/28621_A_5_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000063015-SEZ6
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SEZ6
- Host Animal
- Human
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Seizure related 6 homolog
- Introduction
- The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
- Gene ID
- 124925
- UniProt ID
- Q53EL9
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "SEZ6"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-2594-sdAb | Recombinant Anti-Human SEZ6 VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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