Recombinant Anti-SIGLEC10 Vesicular Antibody, EV Displayed (VS-0425-YC594) (CAT#: VS-0425-YC594)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• SIGLEC10

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Sialic acid binding Ig like lectin 10

• Biological Process
• Adaptive immunity, Cell adhesion, Immunity, Innate immunity

• Cellular Localization
• Cytosol, Plasma membrane, Actin filaments

• Introduction
• SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).

• Alternative Names
• MGC126774, PRO940, SIGLEC-10, SLG2

• Gene ID
• 89790

• UniProt ID
• Q96LC7

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