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SIGLEC10
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- Mouse Anti-SIGLEC10 Recombinant Antibody (HPAB-0260-WJ) (HPAB-0260-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody (HPAB-0262-WJ) (HPAB-0262-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody (HPAB-0261-WJ) (HPAB-0261-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody; scFv Fragment (HPAB-0262-WJ-S(P)) (HPAB-0262-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody; scFv Fragment (HPAB-0261-WJ-S(P)) (HPAB-0261-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody; scFv Fragment (HPAB-0260-WJ-S(P)) (HPAB-0260-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody; Fab Fragment (HPAB-0262-WJ-F(E)) (HPAB-0262-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody; Fab Fragment (HPAB-0261-WJ-F(E)) (HPAB-0261-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-SIGLEC10 Recombinant Antibody; Fab Fragment (HPAB-0260-WJ-F(E)) (HPAB-0260-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Target: SIGLEC10
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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- Anti-SIGLEC10 Immunohistochemistry Kit (VS-0525-XY6579)
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- Species Reactivity: Human
- Target: SIGLEC10
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Kupffer cells, Macrophages, granulocytes, B-cells)
Immune cell specificity
Group enriched (eosinophil, non-classical monocyte, intermediate monocyte)
Cell line specificity
Cell line enhanced (Daudi, HDLM-2, HEL, HMC-1, NB-4, U-698, U-937)
Interaction
Interacts with PTPN6/SHP-1 upon phosphorylation (PubMed:12163025). Interacts with NCF1 (By similarity). Interacts with CD24; the probable CD24:SIGLEC10 complex is proposed to inhibit HGMB1-mediated tissue damage immune response. Interacts with HMGB1; the interaction is dependent on CD24 (PubMed:19264983). Interacts with DDX58, CBL and PTPN11 (By similarity).
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