Recombinant Anti-SLAMF1 Vesicular Antibody, EV Displayed (VS-0425-YC31)
CAT#: VS-0425-YC31
The Recombinant Anti-SLAMF1 Vesicular Antibody, EV Displayed (VS-0425-YC31) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLAMF1-expressed cells or tissues. The SLAMF1 protein enables functions such as SH2 domain binding and virus receptor activity, regulating cytokine production and MAPK cascade from its location in plasma membranes.
Gene Expression
Normal Tissue
Figure 1 High expression in lymph node
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69319/166240_A_8_8_val_selected.jpg
Normal Tissue
Figure 2 Low expression in testis
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69319/166240_A_4_6_val_selected.jpg
Normal Tissue
Figure 3 High expression in appendix.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2438/166244_A_3_2_val_selected.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117090-SLAMF1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLAMF1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Signaling lymphocytic activation molecule family member 1
- Biological Process
- Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Introduction
- Enables several functions, including SH2 domain binding activity; identical protein binding activity; and virus receptor activity. Involved in several processes, including negative regulation of CD40 signaling pathway; negative regulation of cytokine production; and positive regulation of MAPK cascade. Located in extracellular exosome. Is active in plasma membrane.
- Alternative Names
- IPO3; SLAM; CD150; CDw150
- Gene ID
- 6504
- UniProt ID
- Q13291
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1972CQ | Recombinant Rat Anti-Slamf1 Antibody (TC15-12F12.2) | FC, Costim, IP, BL | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3277 | Hi-Affi™ Recombinant Rabbit Anti-SLAMF1 Monoclonal Antibody (DS3277AB) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1059 | CytoStream™ Rabbit Anti-SLAMF1 Recombinant Antibody (VS13-YC1059) | WB, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6618 | Anti-SLAMF1 Immunohistochemistry Kit | IHC |
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