Recombinant Anti-STEAP1 Vesicular Antibody, EV Displayed (VS-0425-YC524)
CAT#: VS-0425-YC524
The Recombinant Anti-STEAP1 Vesicular Antibody, EV Displayed (VS-0425-YC524) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to STEAP1-expressed cells or tissues. STEAP1 is mainly expressed in prostate tissue and is upregulated in various cancer cell lines. The protein is predicted to be a six-transmembrane cell surface antigen found at cell junctions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human lung
Immunohistochemical staining of human lung shows strong cytoplasmic and membranous positivity in pneumocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30985/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30985/123719_B_7_5.jpg
Normal Tissue
Figure 3 Prostate
Glandular cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30985/123719_A_3_5.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (ASC diff, CAPAN-2, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164647-STEAP1/subcellular
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- STEAP1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- STEAP family member 1
- Introduction
- This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
- Alternative Names
- PRSS24, STEAP
- Gene ID
- 26872
- UniProt ID
- Q9UHE8
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Datasheet
MSDS
COA
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See other products for "STEAP1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1961CT | Recombinant Mouse anti-Human STEAP1 Monoclonal antibody (EML1413) | WB | |
| HPAB-N0259-YC | Human Anti-STEAP1 Recombinant Antibody (HPAB-N0259-YC) | FuncS | Humanized IgG |
| HPAB-0487-YJ | Mouse Anti-STEAP1 Recombinant Antibody (HPAB-0487-YJ) | FC, ELISA | Mouse IgG1 |
| HPAB-0488-YJ | Human Anti-STEAP1 Recombinant Antibody (HPAB-0488-YJ) | FC, ELISA | Chimeric (mouse/human) IgG1 |
| HPAB-1208WJ | Mouse Anti-STEAP1 Recombinant Antibody (HPAB-1208WJ) | FC, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0339 | APC-H-2Db/Human STEAP (VSKINRTEM) MHC Tetramer | FCM | |
| MHC-CN1233 | PE-A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer | FCM, IHC | |
| MHC-CN1234 | APC-A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer | FCM, IHC | |
| MHC-CN1235 | FITC-A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer | FCM, IHC | |
| MHC-CN1236 | A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0259-YC-S(P) | Human Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-N0259-YC-S(P)) | FuncS | Humanized scFv |
| HPAB-0487-YJ-S(P) | Mouse Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-0487-YJ-S(P)) | FC, ELISA | Mouse scFv |
| HPAB-0488-YJ-S(P) | Mouse Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-0488-YJ-S(P)) | FC, ELISA | Mouse scFv |
| HPAB-0489-YJ-S(P) | Human Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-0489-YJ-S(P)) | FC, ELISA | Humanized scFv |
| HPAB-1208WJ-S(P) | Mouse Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-1208WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0259-YC-F(E) | Human Anti-STEAP1 Recombinant Antibody; Fab Fragment (HPAB-N0259-YC-F(E)) | FuncS | Humanized Fab |
| HPAB-0487-YJ-F(E) | Mouse Anti-STEAP1 Recombinant Antibody; Fab Fragment (HPAB-0487-YJ-F(E)) | FC, ELISA | Mouse Fab |
| HPAB-0488-YJ-F(E) | Human Anti-STEAP1 Recombinant Antibody; Fab Fragment (HPAB-0488-YJ-F(E)) | FC, ELISA | Fab |
| HPAB-0489-YJ-F(E) | Human Anti-STEAP1 Recombinant Antibody; Fab Fragment (HPAB-0489-YJ-F(E)) | FC, ELISA | Humanized Fab |
| HPAB-1208WJ-F(E) | Mouse Anti-STEAP1 Recombinant Antibody; Fab Fragment (HPAB-1208WJ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY186 | Mouse Anti-STEAP1 scFv-Fc Chimera (VS-0425-FY186) | ELISA, WB, IHC, FC | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6965 | Anti-STEAP1 Immunohistochemistry Kit | IHC |
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