Recombinant Mouse Anti-USP6 Antibody (clone 3C3G2) (CAT#: VS4-CJ153)
This mouse anti-USP6 antibody (clone 3C3G2) is a product that recognizes human USP6. The immunogen of this antibody is recombinant human Ubiquitin carboxyl-terminal hydrolase 6 protein (348aa-535aa). This product was purified by protein G purified and it has been tested for use in ELISA, Western Blot (1:1000-1:5000), Immunofluorescence (1:50-1:200).
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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46969/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46969/if_selected.jpg
Specifications
- Immunogen
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase 6 protein (348aa-535aa)
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human USP6
- Species Reactivity
- Human
- Clone
- 3C3G2
- Applications
- ELISA, WB, IF
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.01M PBS, pH 7.4.
- Preservative
- 0.03% Proclin 300
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot (1:1000-1:5000), Immunofluorescence (1:50-1:200).
Target
- Alternative Names
- HRP1; TRE2; TRE17; Tre-2; TRESMCR; USP6-short
- Gene ID
- 9098
- UniProt ID
- P35125
- Long Name
- Ubiquitin specific peptidase 6
- Sequence Similarities
- Belongs to the peptidase C19 family.
- Cellular Localization
- Cell membrane, Cytoplasm, Endosome, Membrane
- Protein Refseq
- NP_001291213.1; NP_004496.2
- Function
- Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2185CT | Recombinant Mouse anti-Human USP6 Monoclonal antibody (EML868) | WB |
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