Recombinant Mouse Anti-USP6 Antibody (clone 3C3G2) (CAT#: VS4-CJ153)
This mouse anti-USP6 antibody (clone 3C3G2) is a product that recognizes human USP6. The immunogen of this antibody is recombinant human Ubiquitin carboxyl-terminal hydrolase 6 protein (348aa-535aa). This product was purified by protein G purified and it has been tested for use in ELISA, Western Blot (1:1000-1:5000), Immunofluorescence (1:50-1:200).
Specific Inquiry
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46969/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46969/if_selected.jpg
Specifications
- Immunogen
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase 6 protein (348aa-535aa)
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human USP6
- Species Reactivity
- Human
- Clone
- 3C3G2
- Applications
- ELISA, WB, IF
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.01M PBS, pH 7.4.
- Preservative
- 0.03% Proclin 300
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot (1:1000-1:5000), Immunofluorescence (1:50-1:200).
Target
- Alternative Names
- HRP1; TRE2; TRE17; Tre-2; TRESMCR; USP6-short
- Gene ID
- 9098
- UniProt ID
- P35125
- Long Name
- Ubiquitin specific peptidase 6
- Sequence Similarities
- Belongs to the peptidase C19 family.
- Cellular Localization
- Cell membrane, Cytoplasm, Endosome, Membrane
- Protein Refseq
- NP_001291213.1; NP_004496.2
- Function
- Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2185CT | Recombinant Mouse anti-Human USP6 Monoclonal antibody (EML868) | WB |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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