Recombinant Mouse Anti-USP6 Antibody (clone 3C3G2) (CAT#: VS4-CJ153)

• Immunogen
• Recombinant Human Ubiquitin carboxyl-terminal hydrolase 6 protein (348aa-535aa)

• Host Species
• Mouse

• Type
• Mouse IgG1

• Specificity
• Human USP6

• Species Reactivity
• Human

• Clone
• 3C3G2

• Applications
• ELISA, WB, IF

• Conjugate
• Unconjugated

• Purification
• Protein G purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• 50% Glycerol, 0.01M PBS, pH 7.4.

• Preservative
• 0.03% Proclin 300

• Storage
• Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

• Application Notes
• This antibody has been tested for use in ELISA, Western Blot (1:1000-1:5000), Immunofluorescence (1:50-1:200).

• Alternative Names
• HRP1; TRE2; TRE17; Tre-2; TRESMCR; USP6-short

• Gene ID
• 9098

• UniProt ID
• P35125

• Long Name
• Ubiquitin specific peptidase 6

• Sequence Similarities
• Belongs to the peptidase C19 family.

• Cellular Localization
• Cell membrane, Cytoplasm, Endosome, Membrane

• Protein Refseq
• NP_001291213.1; NP_004496.2

• Function
• Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Isotype Control

• MOB-065CQ
• Mouse IgG1 Isotype Control Antibody

Secondary Antibody

• 2RD-A1562-YJ
• Rabbit Anti-Mouse IgG1 Secondary antibody (Clone RM106)

• 2RD-A1460-YJ
• Goat Anti-Mouse IgG1 Secondary antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

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