Recombinant Anti-VSIG4 Vesicular Antibody, EV Displayed (VS-0425-YC23)
CAT#: VS-0425-YC23
The Recombinant Anti-VSIG4 Vesicular Antibody, EV Displayed (VS-0425-YC23) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VSIG4-expressed cells or tissues. The VSIG4 is a protein related to the B7 family of immune regulatory proteins, possibly serving as a negative regulator of T-cell responses and a receptor for complement fragments.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3903/if_selected.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- VSIG4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- V-set and immunoglobulin domain containing 4
- Biological Process
- Complement alternate pathway, Immunity, Innate immunity
- Cellular Localization
- Plasma membrane, Cytosol, Nucleoli
- Introduction
- This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
- Alternative Names
- CRIg, Z39IG
- Gene ID
- 11326
- UniProt ID
- Q9Y279
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Datasheet
MSDS
COA
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See other products for "VSIG4"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2062z | Mouse Anti-VSIG4 Recombinant Antibody (MOB-2062z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| VS4-CJ155 | Recombinant Human Anti-VSIG4 Antibody (clone 12D12) | ELISA | Human IgG1 |
| VS-0723-WK183 | Human Anti-VSIG4 Recombinant Antibody (VS-0723-WK183) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2062z-F(E) | Recombinant Anti-Human VSIG4 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2062z-S(P) | Recombinant Anti-Human VSIG4 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4489 | Rabbit Anti-VSIG4 Recombinant Antibody (clone SI586DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-011LC | Recombinant Alpaca Anti-VSIG4 Single domain Antibody | ELISA | Alpaca VHH |
| HPAB-M0396-YC | Recombinant Alpaca Anti-VSIG4 Single Domain Antibody (HPAB-M0396-YC) | ELISA | Alpaca VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY42 | Human Anti-VSIG4 scFv-Fc Chimera (VS-0325-FY42) | Neut, ELISA, FC | Human IgG1, scFv-Fc |
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