Human Anti-VSIG4 scFv-Fc Chimera (VS-0325-FY42)
CAT#: VS-0325-FY42
The anti-VSIG4 scFv-Fc antibody targets V-set and Immunoglobulin domain-containing protein 4 (VSIG4), a protein involved in immune regulation. It is designed to modulate VSIG4 function, which may have therapeutic implications in autoimmune and inflammatory diseases.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3903/if_selected.jpg
Normal Tissue
Figure 2 Lung
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3903/12486_A_3_4_selected.jpg
Normal Tissue
Figure 3 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26000/55640_A_9_8.jpg
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human VSIG4
- Species Reactivity
- Human
- Applications
- Neutralization, ELISA, Flow Cytometry
- Related Disease
- Autoimmune and inflammatory disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- V-Set And Immunoglobulin Domain Containing 4; Protein Z39Ig; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Ig Superfamily Protein
- Gene ID
- 11326
- UniProt ID
- Q9Y279
- Long Name
- V-Set And Immunoglobulin Domain Containing 4
- Cellular Localization
- Membrane
- Protein Refseq
- NP_001093901.1; NP_001171759.1; NP_001171760.1
- Function
- This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "VSIG4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2062z | Mouse Anti-VSIG4 Recombinant Antibody (MOB-2062z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| VS4-CJ155 | Recombinant Human Anti-VSIG4 Antibody (clone 12D12) | ELISA | Human IgG1 |
| VS-0723-WK183 | Human Anti-VSIG4 Recombinant Antibody (VS-0723-WK183) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2062z-F(E) | Recombinant Anti-Human VSIG4 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2062z-S(P) | Recombinant Anti-Human VSIG4 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4489 | Rabbit Anti-VSIG4 Recombinant Antibody (clone SI586DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-011LC | Recombinant Alpaca Anti-VSIG4 Single domain Antibody | ELISA | Alpaca VHH |
| HPAB-M0396-YC | Recombinant Alpaca Anti-VSIG4 Single Domain Antibody (HPAB-M0396-YC) | ELISA | Alpaca VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC23 | Recombinant Anti-VSIG4 Vesicular Antibody, EV Displayed (VS-0425-YC23) | ELISA, FC, Cell-uptake |
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