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Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The seeds or the resulting amyloid plaques are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold.

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
IP, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, FC, FuncS
Species Reactivity:
human
Type:
scFv-(D-Arg)9
Application:
ELISA, IF, Neut, FuncS
Species Reactivity:
human
Type:
scFv-(+36GFP)
Application:
ELISA, Neut, FuncS
Species Reactivity:
human
Type:
scFv-Tat
Application:
PCA, WB, FuncS
Derivation:
Humanized
Type:
ADCC enhanced antibody
Derivation:
Mouse hybridoma cell line
Species Reactivity:
Human
Application:
ELISA
Derivation:
Humanized
Type:
Antibody
Derivation:
Mouse hybridoma cell line
Species Reactivity:
Human
Application:
ELISA
Host animal:
Mouse
Specificity:
Human
Type:
Mouse antibody
Classification:
Fc glycosylation/Sialylated
Glycosylation site:
Fc region
Glycoform (ratio):
G2F+4 NeuNAc
Host animal:
Mouse
Specificity:
Human
Type:
Mouse antibody
Classification:
Fc glycosylation/Sialylated
Glycosylation site:
Fc region
Glycoform (ratio):
G2F+4 NeuNAc
Host animal:
Mouse
Specificity:
Human
Type:
Mouse antibody
Classification:
Fc glycosylation/Sialylated
Glycosylation site:
Fc region
Glycoform (ratio):
G2F+4 NeuNAc
Host animal:
Mouse
Specificity:
Human
Type:
Mouse antibody
Classification:
Non-glycosylated
Host animal:
Mouse
Specificity:
Human
Type:
Mouse antibody
Classification:
Non-glycosylated
Derivation:
Human
Species Reactivity:
Human
Type:
IgG
Application:
WB, IP, FuncS
Derivation:
Human
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, WB, IP, FuncS
Derivation:
Human
Species Reactivity:
Human
Type:
scFv
Application:
WB, IP, FuncS
Derivation:
Mouse hybridoma cell line
Species Reactivity:
Human
Application:
ELISA
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