Afuco™ Anti-Human ANGPTL3 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-037CL)
Anti-ANGPTL3 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a fully human antibody specifically binds and inhibits or interferes with at least one activity of human angiopoietin-like protein 3 (hANGPTL3). The human anti-hANGPTL3 antibodies are useful in treating diseases or disorders associated with ANGPTL3, such as hyperlipidemia, hyperlipoproteinemia and dyslipidemia, including hypertriglyceridemia, hypercholesterolemia, chylomicronemia, and so forth.
Specific Inquiry
Normal Tissue
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/ihc_selected.jpg
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/ihc_selected.jpg
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78355_B_9_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78355_B_9_5.jpg
Figure 3 Colon
(Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_3.jpg
(Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_9_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_9_4.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_5.jpg
Figure 6 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_4_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_4_6.jpg
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cardiovascular Diseases
Product Property
- Purity
- >95% by HPLC
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- ANGPTL3; angiopoietin-like 3; ANL3; ANG-5; FHBL2; ANGPT
- Gene ID
- 27329
- UniProt ID
- Q9Y5C1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ANGPTL3"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H30 | Anti-Human ANGPTL3 Recombinant Antibody | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0900CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0900CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0901CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0901CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0902CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0902CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0903CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0903CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0904CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0904CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0171 | Hi-Affi™ Rabbit Anti-ANGPTL3 Recombinant Antibody (clone DS171AB) | WB, ICC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-FY | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY) | Inhib | Human IgG4, κ |
| HPAB-0221-FY | Human Anti-ANGPTL3 Recombinant Antibody (clone ANGPTL3-2) | ELISA, Inhib | Human IgG |
| HPAB-0222-FY | Human Anti-ANGPTL3 Recombinant Antibody (clone ANGPTL3-7) | ELISA, Inhib | Human IgG |
| VS-0723-WK210 | Rabbit Anti-ANGPTL3 Recombinant Antibody (VS-0723-WK210) | ELISA, FC | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-FY-S(P) | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY-S(P)); scFv Fragment | Inhib | Human scFv |
| HPAB-0221-FY-S(P) | Human Anti-ANGPTL3 Recombinant Antibody (clone ANGPTL3-2); scFv Fragment | ELISA, Inhib | Human scFv |
| HPAB-0222-FY-S(P) | Human Anti-ANGPTL3 Recombinant Antibody (clone ANGPTL3-7); scFv Fragment | ELISA, Inhib | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-FY-F(E) | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY-F(E)); Fab Fragment | Inhib | Human Fab |
| HPAB-0221-FY-F(E) | Human Anti-ANGPTL3 Recombinant Antibody (clone ANGPTL3-2); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0222-FY-F(E) | Human Anti-ANGPTL3 Recombinant Antibody (clone ANGPTL3-7); Fab Fragment | ELISA, Inhib | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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