Afuco™ Anti-Human ANGPTL3 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-037CL
Anti-ANGPTL3 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a fully human antibody specifically binds and inhibits or interferes with at least one activity of human angiopoietin-like protein 3 (hANGPTL3). The human anti-hANGPTL3 antibodies are useful in treating diseases or disorders associated with ANGPTL3, such as hyperlipidemia, hyperlipoproteinemia and dyslipidemia, including hypertriglyceridemia, hypercholesterolemia, chylomicronemia, and so forth.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78355_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38097/78639_A_4_6.jpg
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cardiovascular Diseases
Product Property
- Purity
- >95% by HPLC
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ANGPTL3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H30 | Anti-Human ANGPTL3 Recombinant Antibody | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0900CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0900CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0901CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0901CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0902CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0902CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0903CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0903CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| TAB-0904CLV-F(E) | Mouse Anti-ANGPTL3 Recombinant Antibody; Fab Fragment (TAB-0904CLV-F(E)) | ELISA, Neut, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0171 | Hi-Affi™ Rabbit Anti-ANGPTL3 Recombinant Antibody (clone DS171AB) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-FY | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY) | Inhib | Human IgG4, κ |
| HPAB-0221-FY | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0221-FY) | ELISA, Inhib | Human IgG |
| HPAB-0222-FY | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0222-FY) | ELISA, Inhib | Human IgG |
| VS-0723-WK210 | Rabbit Anti-ANGPTL3 Recombinant Antibody (VS-0723-WK210) | ELISA, FC | Rabbit IgG |
| VS13-YC50 | Rabbit Anti-ANGPTL3 Recombinant Antibody (VS13-YC50) | WB, IHC-P, IHC-Fr, ICC, IF, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-FY-S(P) | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY-S(P)); scFv Fragment | Inhib | Human scFv |
| HPAB-0221-FY-S(P) | Human Anti-ANGPTL3 Recombinant Antibody scFv Fragment (HPAB-0221-FY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-0222-FY-S(P) | Human Anti-ANGPTL3 Recombinant Antibody scFv Fragment (HPAB-0222-FY-S(P)) | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-FY-F(E) | Human Anti-ANGPTL3 Recombinant Antibody (HPAB-0187-FY-F(E)); Fab Fragment | Inhib | Human Fab |
| HPAB-0221-FY-F(E) | Human Anti-ANGPTL3 Recombinant Antibody Fab Fragment (HPAB-0221-FY-F(E)) | ELISA, Inhib | Human Fab |
| HPAB-0222-FY-F(E) | Human Anti-ANGPTL3 Recombinant Antibody Fab Fragment (HPAB-0222-FY-F(E)) | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY32 | Human Anti-ANGPTL3 scFv-Fc Chimera (VS-0425-FY32) | ELISA | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY375 | Anti-ANGPTL3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY376 | Anti-Mouse ANGPTL3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC15 | Recombinant Anti-ANGPTL3 Eliminating Antibody, pH-Sensitive (VS-0625-YC15) | Antigen-Sweeping In Vivo. | Human IgG1 |
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