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ATP5F1B
Loading...Anti-ATP5F1B Products
- Mouse Anti-ATP5F1B Recombinant Antibody (clone m7A8) (HPAB-J0040-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, IF, IHC
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- Mouse Anti-ATP5F1B Antibody (clone m7A8), mRNA (HPAB-J0040-YC-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Rabbit IgG
- Application: WB, IHC-F, IHC-P, ICC, IF, IP
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- Human Anti-ATP5F1B Recombinant Antibody (clone c7A8) (HPAB-J0041-YC)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, WB, IF, IHC
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- Human Anti-ATP5F1B Recombinant Antibody (clone c7A8); scFv Fragment (HPAB-J0041-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IF, IHC
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- Mouse Anti-ATP5F1B Recombinant Antibody (clone m7A8); scFv Fragment (HPAB-J0040-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IF, IHC
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- Human Anti-ATP5F1B Recombinant Antibody (clone c7A8); Fab Fragment (HPAB-J0041-YC-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, IF, IHC
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- Mouse Anti-ATP5F1B Recombinant Antibody (clone m7A8); Fab Fragment (HPAB-J0040-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, IF, IHC
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- Anti-Rat ATP5F1B Immunohistochemistry Kit (VS-0525-XY625)
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- Species Reactivity: Human, Rat, Canine, Monkey
- Target: ATP5F1B
- Application: IHC
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- Anti-Mouse ATP5F1B Immunohistochemistry Kit (VS-0525-XY624)
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- Species Reactivity: Human, Mouse, Rat
- Target: ATP5F1B
- Application: IHC
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- Anti-ATP5F1B Immunohistochemistry Kit (VS-0525-XY623)
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- Species Reactivity: Human
- Target: ATP5F1B
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal tubular cells, Syncytiotrophoblasts, Proximal tubular cells, Cytotrophoblasts, Hofbauer cells, Extravillous trophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ. Interacts with PPIF. Interacts with BCL2L1 isoform BCL-X(L); the interaction mediates the association of BCL2L1 isoform BCL-X(L) with the mitochondrial membrane F(1)F(0) ATP synthase and enhances neurons metabolic efficiency. Interacts with CLN5 and PPT1. Interacts with S100A1; this interaction increases F1-ATPase activity (By similarity). Interacts with MTLN (PubMed:32243843). Interacts with TTC5/STRAP; the interaction results in decreased mitochondrial ATP production (PubMed:25168243).
Molecular function
Translocase
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
Related Diseases
Morphine Addiction