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BACE2
Loading...Anti-BACE2 Products
- Mouse Anti-BACE2 Antibody (clone Fab1/9), mRNA (PABX-015-mRNA)
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- Species Reactivity: Human
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- Recombinant Mouse Anti-Bace2 Antibody scFv Fragment (Fab1/9) (PABX-015-S (P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, IF, FuncS
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- Human Anti-BACE2 Recombinant Antibody (clone 1/9) (FAMAB-1024CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, IHC
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- Recombinant Anti-human BACE2 Antibody scFv Fragment (MOB-96-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: RIA, ELISA, FuncS
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- Recombinant Human Anti-human BACE2 Antibody Fab Fragment (MHH-96-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, IF, FuncS
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- Recombinant Anti-human BACE2 Antibody Fab Fragment (MOB-96-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, IF, FuncS
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- Recombinant Mouse Anti-Bace2 Antibody Fab Fragment (Fab1/9) (PABX-015-F (E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, IF, FuncS
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- Species Reactivity: Human
- Target: BACE2
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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- Anti-BACE2 Immunohistochemistry Kit (VS-0525-XY678)
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- Species Reactivity: Human
- Target: BACE2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Protein class
Enzymes, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Prostatic glandular cells)
Immune cell specificity
Group enriched (eosinophil, basophil)
Cell line specificity
Cell line enhanced (OE19, SK-BR-3, SK-MEL-30, WM-115)
Interaction
Monomer. Interacts ith RTN3 and RTN4.
Molecular function
Aspartyl protease, Hydrolase, Protease
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