Recombinant Human Anti-human BACE2 Antibody (CAT#: MHH-96)
Recombinant Human Antibody recognises an antigen Human BACE2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-BACE2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-BACE2 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35416/137336_B_7_5.jpg
(Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35416/137336_B_7_5.jpg
Figure 2 Liver
(Hepatocytes
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35416/137336_A_9_4.jpg
(Hepatocytes
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35416/137336_A_9_4.jpg
Figure 3 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35416/137336_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35416/137336_A_6_6.jpg
Figure 4 RNA cell line category: Cell line enhanced (OE19, SK-BR-3, SK-MEL-30, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182240-BACE2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182240-BACE2
Specifications
- Immunogen
- Human beta-site APP-cleaving enzyme 2
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human beta-site APP-cleaving enzyme 2
- Species Reactivity
- Human
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Immunofluorescence; Functional Study
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- BACE2; beta-site APP-cleaving enzyme 2; ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; beta-secretase 2; memapsin-1; theta-secretase; aspartyl protease 1; 56 kDa aspartic-like protease; Down syndrome region aspartic protease; transmembrane aspartic
- Gene ID
- 25825
- UniProt ID
- Q9Y5Z0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-96 | Recombinant Anti-human BACE2 Antibody | WB, IHC, FuncS | IgG |
| PABL-409 | Mouse Anti-BACE2 Recombinant Antibody (clone 19) | ELISA | Mouse IgG |
| FAMAB-1024CQ | Human Anti-BACE2 Recombinant Antibody (clone 1/9) | WB, IHC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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