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BAK1
Anti-BAK1 Recombinant Antibody Products
- Rat Anti-BAK1 Recombinant Antibody (HPAB-0257-YJ) (HPAB-0257-YJ)
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- Species Reactivity: Human
- Type: Rat IgG
- Application: ELISA, Activ, IP
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- Rabbit Anti-BAK1 Recombinant Antibody (clone CBACN-059) (MRO-0152-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
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- Mouse Anti-BAK1 Recombinant Antibody (clone BU9C5) (MOB-0894MZ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, WB
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- Rabbit Anti-BAK1 Recombinant Antibody (VS3-WK1010) (VS3-WK1010)
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC
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- Rat Anti-BAK1 Recombinant Antibody; scFv Fragment (HPAB-0257-YJ-S(P)) (HPAB-0257-YJ-S(P))
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- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, Activ
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- Rat Anti-BAK1 Recombinant Antibody; Fab Fragment (HPAB-0257-YJ-F(E)) (HPAB-0257-YJ-F(E))
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- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, Activ
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Protein class
Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Distal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Formation of the homodimer is zinc-dependent (PubMed:17157251). Forms heterodimers with BCL2 and BCL2L1 isoform Bcl-X(L) (PubMed:9020082). Forms heterooligomers with BAX (PubMed:29531808). Interacts with BCL2A1 (By similarity). Interacts with RTL10/BOP (PubMed:23055042). Interacts with VDAC1 (PubMed:25296756). Interacts with GIMAP3/IAN4 and GIMAP5/IAN5 (PubMed:16509771). (Microbial infection) Interacts with vaccinia virus protein F1. (Microbial infection) Interacts with myxoma virus protein M11L. (Microbial infection) Interacts with Epstein-Barr virus protein BALF1. (Microbial infection) Interacts with adenovirus protein E1B 19K.
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