Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Secreted
Cell type enhanced (Hepatocytes, Cholangiocytes, Leydig cells, Respiratory ciliated cells, Late spermatids)
Not detected in immune cells
Group enriched (ASC diff, ASC TERT1, HSkMC)
Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
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For Research Use Only. Not For Clinical Use.