+ Filter
Loading...
CCN1
Loading...Anti-CCN1 Products
- Anti-CCN1 Immunohistochemistry Kit (VS-0525-XY1072)
-
- Species Reactivity: Human
- Target: CCN1
- Application: IHC
Compare
- Anti-Mouse CCN1 Immunohistochemistry Kit (VS-0525-XY1073)
-
- Species Reactivity: Human, Mouse, Rat
- Target: CCN1
- Application: IHC
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Fibroblasts, Cytotrophoblasts, Adipocytes, Syncytiotrophoblasts, Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, EFO-21, SiHa, TIME, U-251 MG)
Interaction
Interaction with integrins is heparin- and cell-type-dependent and promotes cell adhesion. In skin fibroblasts it binds ITGA6/ITGB1, in endothelial cells, binds ITGAV/ITGB3 and in platelets, ITGA2B/ITGB3. Binds, in vitro, ITGAV/ITGB5.
Molecular function
Growth factor binding, Heparin-binding
More Types Infomation