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CDC27

Anti-CDC27 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


CDC27 (Cell Division Cycle 27) is a Protein Coding gene. Diseases associated with CDC27 include Cervix Carcinoma and Breast Cancer. Among its related pathways are PAK Pathway and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include protein phosphatase binding.
Protein class

Cancer-related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Erythroid cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer. The mammalian APC/C is composed at least of 14 distinct subunits ANAPC1, ANAPC2, CDC27/APC3, ANAPC4, ANAPC5, CDC16/APC6, ANAPC7, CDC23/APC8, ANAPC10, ANAPC11, CDC26/APC12, ANAPC13, ANAPC15 and ANAPC16 that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa; APC/C interacts with FZR1 and FBXO5 (PubMed:26083744, PubMed:25043029). Interacts with RB. Interacts with FAM168B/MANI (By similarity). Interacts with MCPH1 (PubMed:22139841).

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