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CSF2RB
Anti-CSF2RB Recombinant Antibody Products
- Mouse Anti-CSF2RB Recombinant Antibody (VS3-FY2677) (VS3-FY2677)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC, FC, ELISA
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For Research Use Only. Not For Clinical Use.
CSF2RB (Colony Stimulating Factor 2 Receptor Beta Common Subunit) is a Protein Coding gene. Diseases associated with CSF2RB include Surfactant Metabolism Dysfunction, Pulmonary, 5 and Hereditary Pulmonary Alveolar Proteinosis. Among its related pathways are RET signaling and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include receptor activity and interleukin-3 receptor activity.
Protein class
CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (granulocytes, Langerhans cells, Plasma cells, dendritic cells, monocytes, Late spermatids, Extravillous trophoblasts, Macrophages)
Immune cell specificity
Group enriched (basophil, neutrophil)
Cell line specificity
Group enriched (HEL, HMC-1)
Interaction
Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits. Interacts with TMEM102; this interaction occurs preferentially in the absence of CSF2. Interacts with FCER1G; this interaction is direct. Interacts with LYN.
Molecular function
Receptor
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