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CXCL10

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For Research Use Only. Not For Clinical Use.


CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. Diseases associated with CXCL10 include Endotheliitis and Paracoccidioidomycosis. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL9.
CXCL10
Protein class

Cancer-related genes, Human disease related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Basal respiratory cells, Macrophages, Kupffer cells, Glandular and luminal cells, Plasma cells, Langerhans cells)

Immune cell specificity

Group enriched (intermediate monocyte, non-classical monocyte, classical monocyte)

Cell line specificity

Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG, RPMI-8226, RT4, THP-1)

Interaction

Monomer, dimer, and tetramer (PubMed:12737818). Interacts with CXCR3 (via N-terminus) (PubMed:19151743).

Molecular function

Cytokine

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