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DBH

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
Protein class

Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Hepatic stellate cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SH-SY5Y)

Interaction

Homotetramer; composed of two disulfide-linked dimers.

Molecular function

Monooxygenase, Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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