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EGFR & FcγRI
Loading...Anti-EGFR & FcγRI Products
- 10-FnIII scaffold protein anti-Human EGFR (SFN-L003)
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- Scaffold Name: 10-FnIII
- Target: EGFR
- Species Reactivity: Human
- Derivation: Phage display
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For Research Use Only. Not For Clinical Use.
Background
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. Isoform 2 may act as an antagonist of EGF action.
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Related Diseases
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Hepatocellular Carcinoma
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Related Signaling Pathways
JAK-STAT Signaling Pathway
