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Anti-GM-CSF Recombinant Antibody Products
Loading...Anti-GM-CSF Products
- Human Anti-GM-CSF Recombinant Antibody (HPAB-0027LY) (HPAB-0027LY)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: WB
- Human Anti-GM-CSF Recombinant Antibody (clone MOR103) (HPAB-0356-WJ)
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- Derivation: Humanized
- Species Reactivity: Monkey, Human
- Type: Humanized IgG1
- Application: Neut, ELISA
- Human Anti-GM-CSF Recombinant Antibody (clone Plonmarlimab) (VS-0723-WK23)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC
- Rabbit Anti-GM-CSF Recombinant Antibody (VS-0723-WK147) (VS-0723-WK147)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC
- Human Anti-GM-CSF Recombinant Antibody (clone MOR103); scFv Fragment (HPAB-0356-WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Monkey, Human
- Type: Humanized scFv
- Application: Neut, ELISA
- Human Anti-GM-CSF Recombinant Antibody (clone MOR103); Fab Fragment (HPAB-0356-WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Monkey, Human
- Type: Humanized Fab
- Application: Neut, ELISA
- Human Anti-GM-CSF Recombinant Antibody scFv Fragment (HPAB-0027LY-S(P)) (HPAB-0027LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB
- Human Anti-GM-CSF Recombinant Antibody Fab Fragment (HPAB-0027LY-F(E)) (HPAB-0027LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB
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For Research Use Only. Not For Clinical Use.
Creative Biolabs offers premium anti-GM-CSF recombinant antibodies. These rigorously validated reagents are ideal for numerous experiment approaches, such as western blotting, immunohistochemistry, immunofluorescence, ELISA, etc. Our advanced technology ensures high specificity and sensitivity, making them powerful tools for researchers studying cell biology, disease mechanisms, and drug development.
GM-CSF: A Versatile Therapeutic Target for Immunotherapy
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a versatile cytokine produced by various cells in response to immune stimuli. It not only stimulates the production of white blood cells but also enhances their functions, including neutrophil and monocyte recruitment, lymphocyte activation, and promotion of Th1-biased immune responses. While locally produced, GM-CSF can exert its effects systemically, influencing processes such as angiogenesis, allergic inflammation, and autoimmune development. Its multifaceted role in both immune defense and inflammatory disorders makes it a potential therapeutic target.
Alternative Names
Macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; colony-stimulating factor 2; CSF2; GMCSF; CSF.
Background
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients who develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis.
Anti-GM-CSF rAb Products
Creative Biolabs provides a range of recombinant anti-GM-CSF antibodies that have been rigorously designed to give maximal specificity and affinity, allowing them to be utilized in a wide range of applications, from fundamental research to therapeutic development. Furthermore, our recombinant anti-GM-CSF antibodies are available in a range of forms that are well-suited to the diverse demands of global customers. Each antibody we supply comes with reliable validation data and the suggested effective dose. Leveraging our revolutionary platform, we are devoted to offering top-notch research tools to support immunology and cancer research, as well as medicinal development.
Table 1. Featured anti-GM-CSF recombinant antibody products at Creative Biolabs.
| Cat. No. | Product Name | Target Species | Host Species | Applications |
| TAB-180CT | Anti-Human GM-CSF (Granulocyte-macrophage colony stimulating growth factor) Recombinant Antibody (F1) | Human | Human | Neut, Inhib, FC, ELISA |
| TAB-179CT | Human Anti-CSF2 Recombinant Antibody (TAB-179CT) | Human | Human IgG1, κ | ELISA, WB, Neut |
| TAB-178CT | Human Anti-CSF2 Recombinant Antibody (TAB-178CT) | Human, Rabbit, Rhesus | Human IgG1, κ | ELISA, Neut, FC, WB |
| HPAB-0356-WJ | Human Anti-GM-CSF Recombinant Antibody (clone MOR103) | Monkey, Human | Humanized IgG1 | Neut, ELISA |
Creative Quality Control
Creative Biolabs offers a wide range of proven anti-GM-CSF recombinant antibodies, each designed for maximum specificity, stability, and effectiveness. We implement strict quality control measures to ensure our anti-GM-CSF recombinant antibody products meet the highest regulatory standards, making them essential tools for researchers delving into the intricate role of GM-CSF in immunology and cancer research.
Fig.1 WB analysis of anti-GM-CSF antibody
(Cat# TAB-180CT, Creative Biolabs).
Fig.2 DB analysis of anti-GM-CSF antibody
(Cat# TAB-180CT, Creative Biolabs).
Fig.3 ELISA analysis of anti-GM-CSF antibody
(Cat# TAB-180CT, Creative Biolabs).
Fig.4 WB analysis of anti-GM-CSF antibody
(Cat# TAB-179CT, Creative Biolabs).
Fig.5 WB analysis of anti-GM-CSF antibody
(Cat# TAB-178CT, Creative Biolabs).
Customer Reviews
Human Anti-GM-CSF Recombinant Antibody (clone MOR103) (HPAB-0356-WJ)
Human Anti-GM-CSF Recombinant Antibody (clone Plonmarlimab) (VS-0723-WK23)
Rabbit Anti-GM-CSF Recombinant Antibody (VS-0723-WK147) (VS-0723-WK147)
rAb Production
Leveraging innovative genetic engineering techniques, Creative Biolabs produces high-quality anti-GM-CSF antibodies, ensuring a reliable supply to support a diverse array of research applications.
Featured Anti-GM-CSF Recombinant Antibody Production Platforms
Fig.6 Milligram-scale anti-GM-CSF recombinant antibody production.
Fig.7 Gram-scale anti-GM-CSF recombinant antibody production.
rAb Modalities
Creative Biolabs offers a comprehensive suite of premium anti-GM-CSF recombinant antibodies, designed to meet the global research community's diverse needs.
Fig.8 Full-length anti-GM-CSF recombinant antibody production and modalities.
GM-CSF-Targeted Drug Information
Table 2. Public drug targeting GM-CSF.
| Highest Phase | Mechanism of Action | Product Category | Condition | Organization |
|
Merck & Co Merck & Co. (Merck & Co) Novartis Pfizer (Originator) Schering-Plough (Merck & Co) Zenotech Laboratories |
Launched - 1992 |
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Polypeptides, from 41 AA Recombinant proteins |
Neutropenia | |
|
Amgen (Originator) Bayer Bayer Schering Pharma (Bayer) Genzyme (Sanofi Genzyme) Innoventus Project Nat Heart, Lung, and Blood Institute National Cancer Institute Niigata University Nobelpharma Partner Therapeutics Sanofi Sanofi Genzyme Schering AG (Bayer) University of Colorado University of Nebraska |
Launched - 1991 |
Cancer Immunotherapy Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Polypeptides, from 41 AA Recombinant proteins Vaccine Adjuvants |
Acute myeloid leukemia Acute radiation syndrome Acute respiratory distress syndrome (ARDS) AIDS Anemia Cancer, lung Cancer, pancreas Cancer, prostate Crohn's disease Dementia, Alzheimer type Infection, respiratory (lung) Melanoma Melanoma, malignant (cutaneous) Mucositis, chemotherapy- or radiotherapy-induced Neutropenia Parkinson's disease Periodontitis Pulmonary alveolar proteinosis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) Transplantation, bone marrow Transplantation, stem cells, allogenic |
|
| GeneScience Pharmaceuticals | Launched |
Follow-on Products Granulocyte Colony-Stimulating Factor (G-CSF) Polypeptides, from 41 AA Recombinant proteins |
Lesion, skin | |
| Xiamen Amoytop Biotech (Originator) | Launched |
Follow-on Products Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Polypeptides, from 41 AA Recombinant proteins |
Neutropenia | |
|
Humanigen (Originator) KaloBios Pharmaceuticals (Humanigen) National Institute Allergy Infect Dis Telcon RF Pharmaceutical |
Pre-Registered |
Cancer Immunotherapy Human Monoclonal Antibodies |
Asthma Chronic myelomonocytic leukemia Graft-versus-host disease Juvenile myelomonocytic leukemia Neurotoxicity Rheumatoid arthritis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) |
|
|
Apotex (Originator) Cangene (Emergent BioSolutions) Emergent BioSolutions (Originator) |
Pre-Registered |
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Polypeptides, from 41 AA Recombinant proteins |
Agranulocytosis Neutropenia Transplantation, blood stem cells |
|
|
Nobelpharma Savara (Originator) Serendex (Savara) Serendex (Savara) |
Phase III |
Follow-on Products Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Polypeptides, from 41 AA Recombinant proteins |
Acute respiratory distress syndrome (ARDS) Bronchiectasis Fibrosis, cystic Infection, mycobacterial Non-tuberculous mycobacterial infections Pulmonary alveolar proteinosis Respiratory Disorders |
|
| I-Mab Biopharma (Originator) | Phase II/III | Humanized Monoclonal Antibodies |
Autoimmune disease Cytokine release syndrome Inflammatory disorders Osteoarthritis Rheumatoid arthritis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) |
|
|
Barts and the London NHS (Originator) Queen Mary University of London Regenerate Life Science |
Phase II/III |
Autologous Stem Cell Transplantation Polypeptides, from 41 AA Recombinant proteins |
Chronic heart failure | |
|
National Cancer Institute National Cancer Institute (US) (National Cancer Institute) |
Phase II |
Cancer Immunotherapy Cancer Vaccines DNA Vaccines |
Cancer, prostate Cancer, prostate (castration-resistant) |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
Creative Biolabs is a trusted source for high-quality anti-GM-CSF recombinant antibodies. Our well-tested reagents will work better in your research since they are supported by cutting-edge recombinant antibody technology. Our antibodies are your reliable " collaborator " whether you're researching cell signaling pathways or creating innovative treatments. Please don't hesitate to get in touch with us to find a suitable one for your meaningful projects.


Rheumatoid Arthritis
