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HCV E2 protein

Anti-HCV E2 protein Products
- Recombinant Human Anti-HCV E2 Antibody (HPAB-0196CQ) (HPAB-0196CQ)
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- Species Reactivity: HCV
- Type: Human IgG1
- Application: ELISA, Neut
- APC-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer (MHC-LC429)
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- Class: Class I
- Antigen: HCV E2
- Antigen Species: HCV
- Peptide: EYVLLLFLL
- Conjugate: APC
- Anti-HCV E2 Recombinant Antibody Fab Fragment (e137) (MRO-1203LC-F(E))
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- Type: Human antibody
- Application: ELISA
- Recombinant Human Anti-HCV E2 Antibody (HPAB-0197CQ) (HPAB-0197CQ)
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- Species Reactivity: HCV
- Type: Human IgG1
- Application: ELISA, Neut
- AbPlus™ Anti-HCV E2 Magnetic Beads (AP33) (VS-0424-XY82)
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- Target: HCV E2
- Target Species: HCV1, HCV2, HCV3, HCV4, HCV5, HCV6
- Application: IP, Protein Purification
- Human Anti-HCV E2 Protein Antibody, mRNA (HPAB-0234-FY-mRNA) (HPAB-0234-FY-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone HC84-26), mRNA (PABS-0067-mRNA)
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- Species Reactivity: HCV
- Mouse Anti-HCV E2 Protein Antibody, mRNA (PABL-503-mRNA)
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- Species Reactivity: HCV
- Mouse Anti-HCV E2 Protein Antibody (clone MAb24), mRNA (PABC-475-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone HC26AM), mRNA (PABC-282-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone L1), mRNA (FAMAB-0198JF-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone mAb AP33), mRNA (PABL-502-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (PABL-501-mRNA), mRNA (PABL-501-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone HCV1), mRNA (PABL-500-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone HC33.8), mRNA (PABL-499-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone HCV1-C1), mRNA (PABC-474-mRNA)
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- Species Reactivity: HCV genotype 1b
- Mouse Anti-HCV E2 Protein Antibody (clone DAO5), mRNA (PABC-319-mRNA)
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- Species Reactivity: HCV
- Human Anti-HCV E2 Protein Antibody (clone R04), mRNA (MRO-498LC-mRNA)
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- Species Reactivity: HCV virus
- Human Anti-HCV E2 Protein Antibody (clone HC-84.1), mRNA (HPAB-0005-WJ-mRNA)
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- Species Reactivity: Hepatitis C virus
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- Species Reactivity: HCV
- Type: Human IgG1
- Application: ELISA, Neut, FuncS
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- Derivation: Hybridoma
- Species Reactivity: Hepatitis C virus
- Type: Mouse IgG
- Application: ELISA
- Recombinant Human Anti-HCV E2 Antibody (HC-84.1) (HPAB-0005-WJ)
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- Derivation: Immune yeast antibody libraries
- Species Reactivity: Hepatitis C virus
- Type: Human IgG1
- Application: Neut, ELISA, IP, IF
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- Species Reactivity: HCV
- Type: Mouse IgG1, κ
- Application: FuncS, ELISA, Neut, IP
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- Species Reactivity: HCV genotype 1b
- Type: Human IgG1, κ
- Application: ELISA, Neut
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- Species Reactivity: HCV
- Type: Human IgG1
- Application: ELISA, IP, Neut, Inhib, FC
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- Species Reactivity: HCV
- Type: Mouse IgG
- Application: ELISA, FC
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- Species Reactivity: HCV
- Type: Human IgG
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Protein Antibody (e2d066) (HPAB-0156-YJ)
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- Derivation: Phage Library
- Species Reactivity: Hepatitis C virus
- Type: Human IgG1, κ
- Application: ELISA, Inhib
- Recombinant Human Anti-HCV E2 Antibody (MRCT10.V317) (HPAB-1127-CN)
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- Derivation: Phage display library
- Type: Human IgG1, κ
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody (MRCT10.V79) (HPAB-1126-CN)
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- Derivation: Phage display library
- Type: Human IgG1, κ
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody (MRCT10.1) (HPAB-1125-CN)
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- Type: Human IgG1, κ
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody (HPAB-0234-FY) (HPAB-0234-FY)
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- Derivation: Humanized
- Species Reactivity: HCV
- Type: Human IgG
- Application: E, N
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Mouse IgG1, κ
- Application: ELISA, WB
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Mouse IgG1, κ
- Application: ELISA, WB
- Human Anti-HCV E2 Recombinant Antibody (clone 9e1) (FAMAB-0358JF)
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- Derivation: Human phage display scFv library
- Species Reactivity: HCV
- Type: Human IgG
- Application: WB, ELISA, Neut
- Human Anti-HCV E2 Recombinant Antibody (clone L1) (FAMAB-0198JF)
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- Derivation: Human phage display Fab library
- Species Reactivity: HCV
- Type: Human IgG
- Application: WB, ELISA, Neut, IF
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- Species Reactivity: HCV
- Type: Human IgG
- Application: ELISA, FuncS
- Human Anti-HCV E2 Recombinant Antibody (FAMAB-0174WJ) (FAMAB-0174WJ)
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- Species Reactivity: HCV
- Type: Human IgG1
- Application: ELISA, WB, Neut
- Recombinant Human Anti-HCV E1E2 Antibody (clone HC1AM) (VS-0723-XY14)
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- Species Reactivity: HCV
- Type: Human IgG
- Application: ELISA, Neut
- Human Anti-HCV E2 Recombinant Antibody (clone 8D6) (VS-0423-XY36)
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- Species Reactivity: Hepatitis C virus
- Type: Human IgG
- Application: ELISA, IHC
- Human Anti-HCV E2 Recombinant Antibody (clone #55) (FAMAB-0587WJ)
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- Species Reactivity: HCV
- Type: Human IgG1, λ
- Application: ELISA, WB, Neut, IF
- Human Anti-HCV E2 Recombinant Antibody (clone #37) (FAMAB-0586WJ)
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- Species Reactivity: HCV
- Type: Human IgG1, κ
- Application: ELISA, WB, Neut, IF
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Human IgG
- Application: ELISA, WB
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Human IgG
- Application: ELISA, WB
- Recombinant Human Anti-HCV E2 Antibody (MHH-446)
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- Derivation: Human
- Species Reactivity: HCV
- Type: IgG
- Application: FC, WB, FuncS
- Recombinant Anti-HCV E2 Antibody (MOB-446)
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- Derivation: Mouse
- Species Reactivity: HCV
- Type: IgG
- Application: ELISA, WB, Dot, FuncS
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- Species Reactivity: Multiple
- Type: scFv
- Application: ELISA, IHC
- Recombinant Anti-HCV E2 Antibody scFv Fragment (MOB-446-S(P))
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- Derivation: Mouse
- Species Reactivity: HCV
- Type: scFv
- Application: ELISA, IP, FuncS
- Human Anti-HCV E2 protein Recombinant Antibody; scFv Fragment (clone A12) (HPAB-1523WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, WB
- Human Anti-HCV E2 protein Recombinant Antibody; scFv Fragment (clone A8) (HPAB-1522WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, WB
- Human Anti-HCV E2 Recombinant Antibody scFv Fragment (FAMAB-0174WJ-S(P)) (FAMAB-0174WJ-S(P))
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, WB, Neut
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, FuncS
- Human Anti-HCV E2 Recombinant Antibody (clone L1); scFv Fragment (FAMAB-0198JF-S(P))
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- Derivation: Human phage display Fab library
- Species Reactivity: HCV
- Type: Human scFv
- Application: WB, ELISA, FuncS
- Human Anti-HCV E2 Recombinant Antibody (clone 9e1); scFv Fragment (FAMAB-0358JF-S(P))
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- Derivation: Human phage display scFv library
- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, FuncS
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (MRCT10.V317) (HPAB-1127-CN-S(P))
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- Derivation: Phage display library
- Type: Human scFv
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (MRCT10.V79) (HPAB-1126-CN-S(P))
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- Derivation: Phage display library
- Type: Human scFv
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (MRCT10.1) (HPAB-1125-CN-S(P))
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- Type: Human scFv
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HPAB-0234-FY-S(P)) (HPAB-0234-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: HCV
- Type: Human scFv
- Application: E, N
- Recombinant Human Anti-HCV E2 Protein Antibody scFv Fragment (e2d066) (HPAB-0156-YJ-S(P))
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- Derivation: Phage Library
- Species Reactivity: Hepatitis C virus
- Type: Human scFv
- Application: ELISA, Inhib
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Mouse scFv
- Application: ELISA, WB
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Mouse scFv
- Application: ELISA, WB
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- Species Reactivity: HCV
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: HCV genotype 1b
- Type: Human scFv
- Application: ELISA, Neut
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, FC, Neut
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- Species Reactivity: HCV
- Type: Mouse scFv
- Application: ELISA, FC
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HPAB-0197CQ-S(P)) (HPAB-0197CQ-S(P))
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HPAB-0196CQ-S(P)) (HPAB-0196CQ-S(P))
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HPAB-0195CQ-S(P)) (HPAB-0195CQ-S(P))
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- Species Reactivity: HCV
- Type: Human scFv
- Application: ELISA, Neut
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- Derivation: Hybridoma
- Species Reactivity: Hepatitis C virus
- Type: Mouse scFv
- Application: ELISA
- Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HC-84.1) (HPAB-0005-WJ-S(P))
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- Derivation: Immune yeast antibody libraries
- Species Reactivity: Hepatitis C virus
- Type: Human scFv
- Application: ELISA, Neut
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HPAB-0197CQ-F(E)) (HPAB-0197CQ-F(E))
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HPAB-0196CQ-F(E)) (HPAB-0196CQ-F(E))
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, Neut
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HPAB-0195CQ-F(E)) (HPAB-0195CQ-F(E))
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, Neut
- Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (HPAB-0050-WJ-F(E)) (HPAB-0050-WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: Hepatitis C virus
- Type: Mouse Fab
- Application: ELISA
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC-84.1) (HPAB-0005-WJ-F(E))
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- Derivation: Immune yeast antibody libraries
- Species Reactivity: Hepatitis C virus
- Type: Human Fab
- Application: ELISA, Neut
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- Species Reactivity: HCV
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: HCV genotype 1b
- Type: Human Fab
- Application: ELISA, Neut
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, FC, Neut
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- Species Reactivity: HCV
- Type: Mouse Fab
- Application: ELISA, FC
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HPAB-0234-FY-F(E)) (HPAB-0234-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: HCV
- Type: Human Fab
- Application: E, N
- Recombinant Human Anti-HCV E2 Protein Antibody Fab Fragment (e2d066) (HPAB-0156-YJ-F(E))
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- Derivation: Phage Library
- Species Reactivity: Hepatitis C virus
- Type: Human Fab
- Application: ELISA, Inhib
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (MRCT10.V317) (HPAB-1127-CN-F(E))
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- Derivation: Phage display library
- Type: Human Fab
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (MRCT10.V79) (HPAB-1126-CN-F(E))
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- Derivation: Phage display library
- Type: Human Fab
- Application: WB, ELISA, IF
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (MRCT10.1) (HPAB-1125-CN-F(E))
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- Type: Human Fab
- Application: WB, ELISA, IF
- Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (HPAB-0085-WJ-F(E)) (HPAB-0085-WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Mouse Fab
- Application: ELISA, WB
- Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (HPAB-0084-WJ-F(E)) (HPAB-0084-WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Mouse Fab
- Application: ELISA, WB
- Human Anti-HCV E2 Recombinant Antibody (clone 9e1); Fab Fragment (FAMAB-0358JF-F(E))
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- Derivation: Human phage display scFv library
- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, FuncS
- Human Anti-HCV E2 Recombinant Antibody (clone L1); Fab Fragment (FAMAB-0198JF-F(E))
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- Derivation: Human phage display Fab library
- Species Reactivity: HCV
- Type: Human Fab
- Application: WB, ELISA, FuncS
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, FuncS
- Human Anti-HCV E2 Recombinant Antibody Fab Fragment (FAMAB-0174WJ-F(E)) (FAMAB-0174WJ-F(E))
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- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, WB, Neut
- Human Anti-HCV E2 protein Recombinant Antibody; Fab Fragment (clone A12) (HPAB-1523WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, WB
- Human Anti-HCV E2 protein Recombinant Antibody; Fab Fragment (clone A8) (HPAB-1522WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: HCV
- Type: Human Fab
- Application: ELISA, WB
- Recombinant Human Anti-HCV E2 Antibody Fab Fragment (MHH-446-F(E))
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- Derivation: Human
- Species Reactivity: HCV
- Type: Fab
- Application: WB, IHC, FuncS
- Recombinant Anti-HCV E2 Antibody Fab Fragment (MOB-446-F(E))
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- Derivation: Mouse
- Species Reactivity: HCV
- Type: Fab
- Application: ELISA, IP, FuncS
- Recombinant Human Anti-HCV E2 protein Antibody (4c2) (EPAF-1294LC)
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- Species Reactivity: HCV
- Application: ELISA
- Recombinant Mouse Anti-HCV E2 protein Antibody (JS-81) (EPAF-0065LC)
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- Species Reactivity: HCV
- Type: IgG1
- Application: ELISA
- Human Anti-HCV E2 Vaccinal Antibody (VS-0625-XY18) (VS-0625-XY18)
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- Species Reactivity: HCV
- Target: HCV E2
- Host Animal: Human
- Application: ELISA, IF, Neut
- Type: Human IgG
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- Species Reactivity: HCV
- Target: HCV E2 Protein
- Type: Tandem scFv
- Application: ELISA, Neut
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For Research Use Only. Not For Clinical Use.
Background
E2 is the main HCV receptor binding protein and the primary target for broadly neutralizing antibodies (bnAbs). The receptor binding domain (residues 384 to 645), also known as E2 core domain, is modified by up to 11 N-linked glycans and contains several variable regions that increase the genetic diversity of HCV for evasion of the immune system. Crystal structures of E2 from different HCV strains are all very similar, with the E2 core domain consisting of a central immunoglobulin (Ig)β-sandwich fold stabilized by eight disulfides and flanked by N-terminal hypervariable region 1, a front layer, and a C-terminal back layer (residues 597 to 645). The high density of the disulfide bonds contributes to the high thermal stability of E2, although the receptor binding site in recombinant E2 exhibits high conformational flexibility.