Recombinant Human Anti-HCV E2 Antibody (C2)
CAT#: PABL-498
Recombinant Human Antibody (C2) is capable of binding to HCV E2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HCV E2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HCV E2 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody were able to bind to a peptide containing E2 residues 412-422 (C-Epitope I) but not to the linear counterpart. This MAb bound to purified E2 with affinities of about 50 nM, but they were unable to neutralize virus infection.
Specifications
- Immunogen
- HCV E2 envelope glycoprotein
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native HCV E2
- Species Reactivity
- HCV
- Clone
- C2
- Applications
- Can be useful in applications such as: Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- E2; E2 (HCV); HCV E2
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone C2"
- CAT
- Product Name
See other products for "HCV E2 protein"
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|---|---|---|---|
| MRO-476LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-476LC) | ELISA, Inhib | Chimeric (mouse/human) IgG |
| MRO-476LC-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-476LC-S(P)) | ELISA | Mouse scFv |
| MRO-476LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-476LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-477LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-477LC) | ELISA | Humanized IgG1, κ |
| MRO-478LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-478LC) | ELISA | Humanized IgG1, κ |
| MRO-477LC-S(P) | Human Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-477LC-S(P)) | ELISA | Humanized scFv |
| MRO-478LC-S(P) | Human Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-478LC-S(P)) | ELISA | Humanized scFv |
| MRO-479LC-S(P) | Human Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-479LC-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-467LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (7F2) | ELISA | Human antibody |
| MRO-485LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (AB 68) | ELISA | Human antibody |
| MRO-488LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (CBH-4D) | ELISA, WB | Human antibody |
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| MRO-490LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (CBH-4G) | ELISA, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1191LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (MRO-1191LC-S(P)) | ELISA | Mouse Antibody |
| MRO-1192LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (H6D3) | ELISA | Mouse Antibody |
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| MRO-1195LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (G9E1) | ELISA | Mouse Antibody |
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| EPAF-0065LC | Recombinant Mouse Anti-HCV E2 protein Antibody (JS-81) | ELISA | IgG1 |
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| HPAB-0234-FY-S(P) | Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HPAB-0234-FY-S(P)) | E, N | Human scFv |
| HPAB-0156-YJ-S(P) | Recombinant Human Anti-HCV E2 Protein Antibody scFv Fragment (e2d066) | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0005-WJ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC-84.1) | ELISA, Neut | Human Fab |
| HPAB-0050-WJ-F(E) | Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (HPAB-0050-WJ-F(E)) | ELISA | Mouse Fab |
| PFBC-282 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC26AM) | ELISA, Neut | Human Fab |
| HPAB-0084-WJ-F(E) | Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (HPAB-0084-WJ-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0085-WJ-F(E) | Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (HPAB-0085-WJ-F(E)) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-474 | Recombinant Human Anti-HCV E2 Antibody (HCV1-C1) | ELISA, Neut | Human IgG1, κ |
| PABC-475 | Recombinant Mouse Anti-HCV E2 Antibody (MAb24) | FuncS, ELISA, Neut, IP | Mouse IgG1, κ |
| HPAB-0156-YJ | Recombinant Human Anti-HCV E2 Protein Antibody (e2d066) | ELISA, Inhib | Human IgG1, κ |
| HPAB-1125-CN | Recombinant Human Anti-HCV E2 Antibody (MRCT10.1) | WB, ELISA, IF | Human IgG1, κ |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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