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IDO1

Anti-IDO1 Products
- Rabbit Anti-IDO1 Polyclonal Antibody (MRO-1954-CN) (MRO-1954-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
- Rabbit Anti-IDO1 Recombinant Antibody (HPAB-0281-YJ) (HPAB-0281-YJ)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC-P, ICC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
- Mouse Anti-IDO1 Recombinant Antibody (clone 1G1) (VS3-XY842)
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- Species Reactivity: Mouse
- Type: Mouse IgG1
- Application: WB, IP, IF, IHC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, IHC
- AbPlus™ Anti-IDO1 Magnetic Beads (VS-0724-YC394) (VS-0724-YC394)
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- Target: IDO1
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC
- Recombinant Mouse Anti-Human IDO1 Antibody (MOB-2123MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Rabbit Anti-IDO1 Recombinant Antibody; Fab Fragment (HPAB-0281-YJ-F(E)) (HPAB-0281-YJ-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, IHC-P, ICC
- Rabbit Anti-IDO1 Recombinant Antibody; scFv Fragment (HPAB-0281-YJ-S(P)) (HPAB-0281-YJ-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, IHC-P, ICC
- Anti-IDO1 Immunohistochemistry Kit (VS-0325-XY1091)
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- Species Reactivity: Human, Mouse, Rat
- Target: IDO1
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Protein class
Cancer-related genes, Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (monocytes)
Immune cell specificity
Immune cell enriched (eosinophil)
Cell line specificity
Cell line enriched (EFO-21)
Interaction
Monomer.
Molecular function
Dioxygenase, Oxidoreductase
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