Mouse Anti-IDO1 Recombinant Antibody (clone 19C5) (CAT#: VS11-QX79)
This product is a recombinant mouse antibody that recognizes IDO1. This antibody can be used for the following applications: ELISA, IHC. Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the initial rate-limiting step in the degradation of the essential amino acid tryptophan along the kynurenine pathway.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23072/1830_D10_66_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23072/1830_D10_66_selected.jpg
Figure 2 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, cytosol & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23149/1830_C10_63_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, cytosol & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23149/1830_C10_63_selected.jpg
Figure 3 Placenta
(High expression in placenta)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23149/51465_A_1_7_val_selected.jpg
(High expression in placenta)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23149/51465_A_1_7_val_selected.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23072/51461_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23072/51461_A_4_6.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23149/51465_A_9_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23149/51465_A_9_8.jpg
Figure 6 Colon
(Enterocytes - Mucosal lymphoid cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23072/51461_A_9_3.jpg
(Enterocytes - Mucosal lymphoid cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23072/51461_A_9_3.jpg
Figure 7 RNA cell line category: Cell line enriched (EFO-21)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131203-IDO1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131203-IDO1
Specifications
- Immunogen
- Recombinant human IDO1 protein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human IDO1
- Species Reactivity
- Human
- Clone
- 19C5
- Applications
- ELISA, IHC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- Indoleamine 2,3-Dioxygenase 1
- Gene ID
- 3620
- UniProt ID
- P14902
- Long Name
- Indoleamine 2,3-dioxygenase 1
- Sequence Similarities
- Belongs to the indoleamine 2,3-dioxygenase family.
- Cellular Localization
- Nucleoplasm, Vesicles, Mitochondria, Cytosol
- Function
- Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2702z | Mouse Anti-IDO1 Recombinant Antibody (clone 34C10) | WB, IHC | Mouse IgG2a |
| MOB-2123MZ | Recombinant Mouse Anti-Human IDO1 Antibody | WB | Mouse antibody |
| HPAB-0281-YJ | Rabbit Anti-IDO1 Recombinant Antibody (HPAB-0281-YJ) | ELISA, IHC-P, ICC | Rabbit IgG |
| VS3-XY842 | Mouse Anti-IDO1 Recombinant Antibody (clone 1G1) | WB, IP, IF, IHC | Mouse IgG1 |
| VS3-FY724 | Recombinant Rabbit Anti-IDO1 Antibody (clone R03-5D4) | WB, IHC-Fr, IHC-P, ICC, IF, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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