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IL19

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For Research Use Only. Not For Clinical Use.


Background

Interleukin-19 (IL-19) is a cytokine from the IL-10 family that acts as a negative feedback regulator to limit pro-inflammatory responses by macrophages and microglia, particularly in neuroinflammatory conditions like multiple sclerosis. It suppresses antigen presentation and Th17 cell expansion, playing a protective role in autoimmune diseases.
Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Basal respiratory cells, Club cells, Glandular and luminal cells, Ionocytes, Breast glandular cells, Endometrial ciliated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (BJ hTERT+)

Molecular function

Cytokine

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