Anti-KRAS Recombinant Antibody Products

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Anti-KRAS Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs offers a premier selection of innovative recombinant antibodies targeting KRAS, playing a vital role in advancing biomedical science. Through the use of cutting-edge technology platforms, we ensure that each product adheres to rigorous standards of quality, consistency, and performance. Our extensive catalog reflects our unwavering commitment to driving scientific progress, with each antibody solution engineered for outstanding reliability and value. In addition to delivering top-tier reagents, we provide expert technical support to guide researchers throughout their experimental journey. Partnering with Creative Biolabs means accessing not only advanced tools but also a trusted ally committed to the success of your research.

KRAS: A Pivotal Target in Cancer Progression and Precision Oncology

KRAS is a well-established oncogene that plays a critical role in the development and progression of various cancers, including pancreatic, colorectal, and non-small cell lung cancer. As part of the RAS family of GTPases, KRAS regulates essential cellular functions such as proliferation, differentiation, and survival. Mutations in the KRAS gene often lead to uncontrolled cell signaling, contributing to tumor growth and resistance to therapy. Due to its high mutation frequency and central role in oncogenic pathways, KRAS has become a major focus in cancer research and drug development. Targeting KRAS-driven signaling offers promising therapeutic potential, particularly in tumors previously considered undruggable.

Alternative Names

Complement NS; NS3; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; c-Ki-ras2

Background

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Anti-KRAS rAb Products

We are dedicated to accelerating scientific advancement by providing premium anti-KRAS recombinant antibodies, combining exceptional performance, cost-effectiveness, and reliable technical guidance. Our goal is to empower researchers with the tools and support they need to drive meaningful discoveries.

Customer Reviews

Excellent

A**on
Mouse Anti-KRAS Recombinant Antibody (clone 23A6) (CAT#: MOB-1225z)

Used it for Western blot on A549 cell lysates. Clear, specific bands with minimal background. Also tested in flow cytometry on HCT116 cells with decent signal. Overall, a reliable antibody for basic KRAS detection work.

12/Feb/2023

Excellent

M**ez
Recombinant Mouse Anti-Human KRAS Antibody (CAT#: MOB-1757MZ)

Evaluated its performance in Western blot as well as flow cytometry. Used A549 and HCT116 cell lines for validation. In Western blot, the antibody produced clear bands at the expected size with low background. For flow cytometry, the signal was detectable and consistent, though some optimization was needed for staining conditions. Overall, the antibody performed reliably for basic applications. Good option for routine KRAS detection, but make sure to validate conditions for your specific setup.

15/Aug/2024

rAb Production

With years of experience in developing and optimizing recombinant antibodies, we are able to offer high-quality products with consistent performance. Our efficient processes and commitment to excellence ensure timely delivery and dependable service tailored to researchers' needs.

Featured Anti-KRAS Recombinant Antibody Production Platforms
Fig.1 Milligram-scale recombinant antibody production.

Fig.2 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to providing researchers with a diverse selection of cutting-edge recombinant antibodies in multiple formats. With extensive expertise in recombinant antibody technologies, we employ a variety of advanced engineering techniques. Additionally, we offer exceptional custom engineering services designed to meet the unique requirements of your research.

Fig.3 Full Length Anti-KRAS Recombinant Antibody Production and Modalities.

Drug Information Targeting KRAS

Table 1. Therapeutic approaches targeting KRAS in clinical development.

If you need further details about the KRAS target, don't hesitate to contact us by phone or email. Our expert team is happy to help with any questions or issues you may encounter in your research, providing the support you need for a successful outcome.