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LAT
Anti-LAT Recombinant Antibody Products
- Recombinant Human Anti-LAT Antibody (G10) (HPAB-J0168-YC)
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- Species Reactivity: S. epidermidis
- Type: Human IgG
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody (D3) (HPAB-J0167-YC)
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- Species Reactivity: S. epidermidis
- Type: Human IgG
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody (C10) (HPAB-J0166-YC)
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- Species Reactivity: S. epidermidis
- Type: Human IgG
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody (A1) (HPAB-J0165-YC)
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- Species Reactivity: S. epidermidis
- Type: Human IgG
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody scFv Fragment (G10) (HPAB-J0168-YC-S(P))
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- Species Reactivity: S. epidermidis
- Type: Human scFv
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody scFv Fragment (D3) (HPAB-J0167-YC-S(P))
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- Species Reactivity: S. epidermidis
- Type: Human scFv
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody scFv Fragment (C10) (HPAB-J0166-YC-S(P))
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- Species Reactivity: S. epidermidis
- Type: Human scFv
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody scFv Fragment (A1) (HPAB-J0165-YC-S(P))
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- Species Reactivity: S. epidermidis
- Type: Human scFv
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody Fab Fragment (C10) (HPAB-J0166-YC-F(E))
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- Species Reactivity: S. epidermidis
- Type: Human Fab
- Application: ELISA
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- Recombinant Human Anti-LAT Antibody Fab Fragment (A1) (HPAB-J0165-YC-F(E))
-
- Species Reactivity: S. epidermidis
- Type: Human Fab
- Application: ELISA
Compare
- Recombinant Human Anti-LAT Antibody Fab Fragment (G10) (HPAB-J0168-YC-F(E))
-
- Species Reactivity: S. epidermidis
- Type: Human Fab
- Application: ELISA
Compare
- Recombinant Human Anti-LAT Antibody Fab Fragment (D3) (HPAB-J0167-YC-F(E))
-
- Species Reactivity: S. epidermidis
- Type: Human Fab
- Application: ELISA
Compare
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein class
Disease related genes, Plasma proteins, RAS pathway related proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (NK-cells, T-cells, dendritic cells, granulocytes, Macrophages)
Immune cell specificity
Group enriched (T-reg, basophil, memory CD8 T-cell, gdT-cell, memory CD4 T-cell, naive CD4 T-cell, naive CD8 T-cell, MAIT T-cell, NK-cell)
Cell line specificity
Cell line enhanced (HEL, HMC-1, MOLT-4)
Interaction
When phosphorylated, interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2, GRAP, GRAP2, PLCG1 and PLCG2. Interacts indirectly with CBL, SOS, VAV, and LCP2. Interacts with SHB, SKAP2 and CLNK (By similarity). Interacts with FCGR1A. Interacts with GRB2, PLCG1 and THEMIS upon TCR activation in thymocytes (By similarity). Interacts with THEMIS2 (By similarity).
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